| Quarter (USD) | Sep 24 | Mar 24 | Dec 23 | Sep 23 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Annual (USD) | Dec 23 | Dec 22 | Dec 21 | Dec 20 | |
|---|---|---|---|---|---|
| Revenue | |||||
| Cost of revenue | |||||
| Operating income | |||||
| Operating margin | |||||
| Net income | |||||
| Net profit margin | |||||
| Cash on hand | |||||
| Change in cash | |||||
| Diluted EPS |
| Cash burn rate (est.) | Burn method: Change in cash | Burn method: Operating income | Burn method: FCF (opex + capex) | Last Q | Avg 4Q | Last Q | Avg 4Q | Last Q | Avg 4Q |
|---|---|---|---|---|---|---|
| Cash on hand (at last report) | 78.80 mm | 78.80 mm | 78.80 mm | 78.80 mm | 78.80 mm | |
| Cash burn (monthly) | 5.20 mm | 2.66 mm | 21.59 mm | 17.91 mm | 9.95 mm | |
| Cash used (since last report) | 14.55 mm | 7.44 mm | 60.49 mm | 50.16 mm | 27.87 mm | |
| Cash remaining | 64.24 mm | 71.36 mm | 18.31 mm | 28.63 mm | 50.93 mm | |
| Runway (months of cash) | 12.4 | 26.9 | 0.8 | 1.6 | 5.1 | |
| 13F holders | Current |
|---|---|
| Total holders | 167 |
| Opened positions | 27 |
| Closed positions | 28 |
| Increased positions | 55 |
| Reduced positions | 52 |
| 13F shares | Current |
|---|---|
| Total value | 616.33 bn |
| Total shares | 123.82 mm |
| Total puts | 861.90 k |
| Total calls | 584.70 k |
| Total put/call ratio | 1.5 |
| Largest owners | Shares | Value |
|---|---|---|
| Invus Global Management | 12.83 mm | $121.29 mm |
| Siren, L.L.C. | 11.26 mm | $90.19 bn |
| Artal International S.C.A. | 10.56 mm | $0.00 |
| FMR | 10.20 mm | $81.67 bn |
| T. Rowe Price | 8.65 mm | $69.32 mm |
| Samsara BioCapital | 7.85 mm | $64.87 mm |
| Samsara BioCapital | 6.79 mm | $54.38 bn |
| BlackRock | 6.16 mm | $49.31 bn |
| Redmile | 5.24 mm | $41.96 bn |
| Polaris Venture Partners VI | 4.05 mm | $0.00 |
| Date | Owner | Security | Transaction | Code | Indirect | 10b5-1 | $Price | #Shares | $Value | #Remaining |
|---|---|---|---|---|---|---|---|---|---|---|
| 10 Dec 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 41.65 | 1,600,000 | 66.64 mm | 9,250,005 |
| 25 Nov 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 40.98 | 149 | 6.11 k | 10,850,005 |
| 25 Nov 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 40.139 | 30,683 | 1.23 mm | 10,850,154 |
| 25 Nov 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 39.5104 | 126,442 | 5.00 mm | 10,880,837 |
| 25 Nov 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 38.4321 | 43,887 | 1.69 mm | 11,007,279 |
| 25 Nov 24 | Invus Public Equities | Common Stock | Sell | Dispose S | No | No | 37.6311 | 208,272 | 7.84 mm | 11,051,166 |
| 25 Nov 24 | Jing L. Marantz | Common Stock | Sell | Dispose S | No | Yes | 40.72 | 200 | 8.14 k | 72,855 |
| 25 Nov 24 | Jing L. Marantz | Common Stock | Sell | Dispose S | No | Yes | 39.9285 | 3,075 | 122.78 k | 73,055 |
| 25 Nov 24 | Jing L. Marantz | Common Stock | Sell | Dispose S | No | Yes | 39.2543 | 2,100 | 82.43 k | 76,130 |
| 25 Nov 24 | Jing L. Marantz | Common Stock | Sell | Dispose S | No | Yes | 38.041 | 1,000 | 38.04 k | 78,230 |
