Structure Therapeutics (GPCR)

Annapurna Bio Pty Limited • Annapurna Bio, Inc. • Basecamp Bio Hong Kong Limited • Basecamp Bio Inc. • Basecamp Bio USA Inc. • Gasherbrum Bio, Inc. • Lhotse Bio, Inc. • Shanghai Basecamp Biotechnology Co., Ltd. • Shanghai ShouTi Biotechnology Co., Ltd. • ShouTi Hong Kong Limited ...

IRS number

981480821

GPCR stock data

1M 3M 6M 1Y

Analyst ratings and price targets

Last 3 months

Latest filings (excl ownership)

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8-K

Structure Therapeutics Announces Selection of Lead Oral Small Molecule Amylin Receptor Agonist ACCG-2671 for the Treatment of Obesity

13 Nov 24

Structure Therapeutics Reports Third Quarter 2024 Financial Results and Recent Highlights

13 Nov 24

8-K

Structure Therapeutics Strengthens Executive Team with Promotion of Blai Coll, M.D., Ph.D. to Chief Medical Officer and Appointment of Ashley Hall, J.D. as Chief Development Officer

17 Sep 24

8-K

Departure of Directors or Certain Officers

27 Aug 24

8-K

Submission of Matters to a Vote of Security Holders

27 Jun 24

424B4

Prospectus supplement with pricing info

6 Jun 24

EFFECT

Notice of effectiveness

6 Jun 24

S-1MEF

Registration of additional securities for an S-1

Latest ownership filings

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SC 13G/A

RA CAPITAL MANAGEMENT, L.P.

14 Nov 24

SC 13G

JANUS HENDERSON GROUP PLC

14 Nov 24

SC 13G/A

Avoro Capital Advisors LLC

14 Nov 24

SC 13G

Capital Research Global Investors

WELLINGTON MANAGEMENT GROUP LLP

Financial summary

Financial statements Chart GPCR financial data

Quarter (USD)	Sep 24	Mar 24	Dec 23	Sep 23
Revenue
Cost of revenue
Operating income
Operating margin
Net income
Net profit margin
Cash on hand
Change in cash
Diluted EPS

Annual (USD)	Dec 23	Dec 22
Revenue
Cost of revenue
Operating income
Operating margin
Net income
Net profit margin
Cash on hand
Change in cash
Diluted EPS

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	172.13 mm	172.13 mm	172.13 mm	172.13 mm		172.13 mm
Cash burn (monthly)	(no burn)	(no burn)	15.28 mm	11.25 mm		6.36 mm
Cash used (since last report)	n/a	n/a	42.77 mm	31.49 mm		17.81 mm
Cash remaining	n/a	n/a	129.36 mm	140.64 mm		154.32 mm
Runway (months of cash)	n/a	n/a	8.5	12.5		24.2

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q3 2024

GPCR institutional ownership history Ownership history

13F holders	Current	Prev Q	Change
Total holders	161	174	-7.5%
Opened positions	26	59	-55.9%
Closed positions	39	13	+200.0%
Increased positions	68	63	+7.9%
Reduced positions	33	33	–

13F shares	Current	Prev Q	Change
Total value	2.53 tn	2.20 tn	+14.7%
Total shares	73.35 mm	71.94 mm	+2.0%
Total puts	330.10 k	364.99 k	-9.6%
Total calls	414.20 k	1.06 mm	-60.9%
Total put/call ratio	0.8	0.3	+131.3%

Largest owners	Shares	Value	Change
Biotechnology Value Fund L P	12.66 mm	$329.17 mm	0.0%
Wellington Management	7.77 mm	$341.02 bn	+2.9%
FMR	6.13 mm	$268.98 bn	+6.7%
JHG Janus Henderson	3.96 mm	$173.62 bn	+18.0%
Capital Research Global Investors	3.53 mm	$154.95 bn	+12.7%
Driehaus Capital Management	2.53 mm	$110.89 bn	-2.0%
FHI Federated Hermes	2.41 mm	$105.85 bn	+0.2%
BVF	2.24 mm	$98.27 bn	-10.0%
T. Rowe Price	2.08 mm	$91.50 mm	-9.9%
Ra Capital Management	1.90 mm	$83.25 bn	0.0%

Largest transactions	Shares	Bought/sold	Change
Adage Capital Partners GP, L.L.C.	250.00 k	-963.10 k	-79.4%
BLK BlackRock	0.00	-943.02 k	EXIT
Point72 Asset Management	1.24 mm	+870.59 k	+236.8%
Alyeska Investment	7.66 k	-699.73 k	-98.9%
AMP Ameriprise Financial	1.10 mm	+690.61 k	+169.7%
BLK BlackRock	680.10 k	+680.10 k	NEW
Avidity Partners Management	430.90 k	-644.10 k	-59.9%
JHG Janus Henderson	3.96 mm	+602.61 k	+18.0%
Vestal Point Capital	1.15 mm	+590.00 k	+105.4%
Capital Research Global Investors	3.53 mm	+399.14 k	+12.7%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

GPCR insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
18 Sep 24	Ashley Hall	Ordinary Shares	Grant	Acquire A	No	No	0	67,290	0.00	67,290
18 Sep 24	Ashley Hall	Share option Ordinary Shares	Grant	Acquire A	No	No	12.75	82,890	1.06 mm	82,890
18 Sep 24	Crespo Blas Coll	Ordinary Shares	Grant	Acquire A	No	No	0	90,600	0.00	102,600
18 Sep 24	Crespo Blas Coll	Share option Ordinary Shares	Grant	Acquire A	No	No	12.75	111,000	1.42 mm	111,000