Meeker David P

Date	Company	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
27 Aug 24	TRVI Trevi Therapeutics	Common Stock	Sell	Dispose S	No	No	2.9314	4,555	13.35 k	352,489
27 Aug 24	TRVI Trevi Therapeutics	Common Stock	Option exercise	Acquire M	No	No	1.43	4,555	6.51 k	357,044
27 Aug 24	TRVI Trevi Therapeutics	Stock Option Common Stock	Option exercise	Dispose M	No	No	1.43	4,555	6.51 k	0
13 Jun 24	TRVI Trevi Therapeutics	Nonstatutory Stock Option Common Stock	Grant	Acquire A	No	No	2.77	30,000	83.10 k	30,000
19 Mar 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	39.22	45,494	1.78 mm	174,605
16 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Grant	Acquire A	No	No	0	99,000	0.00	220,099
16 Feb 24	RYTM Rhythm Pharmaceuticals	Stock Option Common Stock	Grant	Acquire A	No	No	49.23	259,000	12.75 mm	259,000
16 Feb 24	RYTM Rhythm Pharmaceuticals	RSU Common Stock	Grant	Acquire A	No	No	0	85,000	0.00	85,000
1 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Sell	Dispose S	No	Yes	45.06	4,361	196.51 k	121,099
1 Feb 24	RYTM Rhythm Pharmaceuticals	Common Stock	Option exercise	Acquire M	No	No	0	14,125	0.00	125,460

Data from 3, 4 and 5 filings. Values as filed, not updated for current price.