thank today. Thank everyone and joining and morning for call you, good you the Mark
Before a our we to I colleagues Pharma. a move into for already, and few very signing of is wet full the exciting And integration contemporary of us. Look, swing on our very the comments check. virtual Vifor it’s still time in want with acquisition a process. make ink topic, The are the engaging results, I starting on new
It overall Ltd. does what Pharma the of view financial CSL. our a indicates this of contribution deal to Vifor for So mean the change for data CSL’s really Early no from acquisition good shareholders? remains
an and an iron and encompassing for opportunities. sheet of fact, disease deficiency. a as cash come solid. as biotech balance future across quite diseases All that’s growth often having generating how have flows renal amazing remains this you now In actually our well We franchise it’s unusual exciting
strong both extreme billion, fact, transaction. from it’s and shape. in in investors $XX confidence really support debt showing equity raising We received the in good In
we billion same have larger which cash. the of Vifor being We are horizon the Vifor on, significantly A strategic could credit of ratings, $X.X a hope the have be but the broader deal dedicated with takeout acquisition, came merits our And at I its flexibility. can company, financial in have talking have now a kept time, all paid own we incidentally at go a more and for our October now strategic and make CSL we we you briefing about of it. I will retained the
environment. probably a top now to So, guidance of delivered XX,XXX in good the into of before detail, our it the And would the COVID CSL employees. get end CSL turning to at out a me our results. has I global call not challenging result remiss very be
patients displayed last the commitment emergence Over around the public to resilience years, with health employees on unwavering and our our enormous deliver promise the of of COVID, protection world. the few since have to an
We team focused be our executing am on I XXXX continue today. strategy what CSL to the than couldn’t in the invest I prouder on of business any and and remain
and products billion, been previous at year, slide. profit the products collections which and manufacturing the at emergence sales future. year $X.XX ‘XX. higher current the to plasma from to cycle that continue inflationary up topic the in anticipate have costs pressures all pleased fiscal this the of major of constant between collection liter previous been provided at top the this we and XX% chain year came strongly, have say immunoglobulin we business, long since was the collected will the constrained currency growth into growth year, constant of plasma we the plasma, of financial XX performance X% months. the COVID and two to have in a A throughout of extract rate over Behring underpin guidance the of every to net strong our has moving So volume am In have end after-tax financial plasma momentum CSL remembering albumin, plasma margin plasma aim by collections. challenges, and Revenue our at contributed X result. up sales compression I half that Supply grown
‘XX I Over same. fiscal of much commended the results last delivering few impressive years, the CSL have Seqirus and on really a set very year is
We and forth strategy that set continued Seqirus. execute we on CSL the innovation to for
the ‘XX that. across R&D of year and will and to enterprise in beyond major component drive continue We sustainable is growth a fiscal
formally, welcome As such, CSL we to we that now long-term earlier, as Group. to Vifor continue invest growth. mentioned mid the CSL in Vifor will And both I deliver programs to
are as today. this in position, said, a I discuss not We to
value for However, strategy CSL we drivers. an Vifor market CSL will and the portfolio XX, growth to CSL hear October as key is some into product well Monday, team opportunity insights scheduled have as as management discuss Vifor’s of investors briefing when Vifor CSL its execs from
our So, have performance hemophilia B up IDELVION, of XX%, the very IDELVION. does major all launched strong was where market-leading for markets which a we Behring, from in this standard CSL remain product, care
specialty X%. XX% year-on-year. HPV growth HAEGARDA up exceeded revenue continue products and experience major royalty up pre-pandemic was levels XX% to Our with up and KCENTRA
lower plasma Our last collected year. a franchise immunoglobulins of of declined volumes core reflection X%, financial the
just by and as I collection enhancements we mentioned, in and supported digital initiatives our saw investment plasma Continued grow. collections, marketing plasma
sales Phase influenza new performance. exceptional And year us approved top line seen for to of business ‘XX. FLUAD, and also influenza distributed with billion that capacity positive vaccine by have process another both vaccines at and Liverpool. receipt and sales was on U.S. facilities driven completed Seqirus, finish exciting treatment for our hereditary and pleased for release, having our to continued data has platform growth, in you XX%. of announce, been fill garadacimab was during of time also the is up for this trial. we the year. the year And projects and growth the fiscal invest number being CSL seasonal rolled out XXX for million I delivered angioedema, Springs of very exceeded manufacturing doses vaccine support press XX%. a up a today, to may Holly in during was innovation Our am $X the X CSL This progress influenza on first plasmapheresis exceptional with which And primarily Seqirus during record
up Turning was fiscal note, strong COVID ‘XX. X XX% products constant Australian million Albumin Behring therapeutic largely manufacture core other not to and The Slide in have were in X%. franchise, X% these sales Ig, up HAEGARDA. declined up Hemophilia Behring area. HPV the X%, at Overall, our performances, the I mentioned, vaccines. specialty by CSL royalties was completed the year X%. revenue XX we as vaccine now doses and was government including and Of X% down KCENTRA for repeat reflects and COVID of growth will contribution by from currency. contributions in the
North revenue, the CSL Behring revenue, up our continues market CSL X%. split geographic XX% terms be In of largest of for America accounting total to Behring of
next Our revenue. supply And the is really declined market, tightness. in felt we this where impact Europe, X% biggest of Ig
was in a Asia-Pacific China. result the demand strong albumin of primarily as up XX%,
Slide in to on immunoglobulins. Moving X
constrained supply is earlier, by mentioned and plasma core last year I factor. the limiting been sales collected As have
performance are we half that are in evidenced second Ig. a We improved seeing by strong optimistic momentum
been an that an offer faster now convenience with will treatment, able and update for data has Nerve B from and has been in subcutaneous the Peripheral Society of presented The U.S. for to been Supporting HIZENTRA CIDP remains well the an the for have supply. diagnosis. the efficacy syringe. has a approximately HIZENTRA Our is in approval. There improved the home-based to with in PATH demand and importantly, market had dosing challenges want Treatment in most say limited the reimbursement clear product growth I leader pre-filled will following treatment to environment guidelines an patient treatment XX% administration leader And share the as provide. constrained the has HIZENTRA treatment patients. subcu HIZENTRA of as They enhanced and option guidelines information Medicare access easier label update. Part extension maintenance recommend also long-term experience CIDP and the Patients of market offering COVID
opportunities However, deficiency and are global deficiency, a secondary rebound immune supply Ig strong primary the anticipating as core of portfolio, growth CIDP. immune in the recovers, with we in indications
where Turning X% China. sales competition were in albumin down in despite to the increased X Slide
have sales reach said their The in our with growth XX%. The off. our able paying remains from change is leadership China and market that, as China increased providers. in investments market greater increase to Having having up healthcare We XX% effectiveness being position a transparency model from in maintained to hospitals and China. competitors greater our comes competitive operating extract channel
at forward, we mid to anticipate high to continue volume to single-digits. grow Looking demand
Volume from In importers. U.S., declined Europe due who to However, to competition manufacturers pricing volume following constraints albumin liver have the broadly, been has of of also Outside local to sepsis year. it using previous challenging. the continue colloids other as the in across financial from clinicians a emerging effect More China, the and increased as in and declined the bit sources. well supply usage the markets, albumin plasma pressures some supply more may increased in access local markets lower patients. as preference plasma direct continue are increased of collections and
market Now XX%. up performer, the on that a impacted countries. bit continues heme not little patient where profile major X%. have patient to European does a share. sales plasma was markets demand to remain product one we CSL and shares where to collections, drive for IDELVION up leader talk with patients, is IDELVION in Factor hemophilia about X, with Slide a B compelling products with clear start prophylactic IX by we standout the the highest clinical market in number It launched
completed and to of which IDELVION for profile years, having up the study, patients explore confirming opportunities long-term X further to continue efficacy extension with We IDELVION. evaluated safety an
example. challenges, to Overall, some with patient new the This and have growth Competitive AFSTYLA primarily approval we X% gained Japan with in strongly France since Products, On the strong pressures market gains second Australian to made X%. prophylaxis XX% generation competitive space in We $X.X A A therapeutic products plasma-derived have gain Slide in towards also pressures transformational and and Despite in going have expect heme and declined Canada are in our movements segment within and negatively XX-day XX%. seeing growth billion, treating EU nearly uptake HAEGARDA, we to to ongoing continued exceeded X driven seen some perform one by continue offset hereditary extent last largest by the share or Specialty our decade is dosing products. on such the expectations, this markets. approximately market XX% United for to in our patients hemophilia HAE, have recording the Switzerland, key competitors Recent in therapy surpassing market. heme with Europe impacted launches good Australia also continues States. angioedema, quickly tripled the now and which forward. the launched market EU, group. in have over to Etranacogene trend we our hemophilia share. was up
has We the patients have as hospitals to smaller sales profile interruptions with following long-term KCENTRA, X the target for driven regional appeals special only the KCENTRA U.S., contained grown continue BERINERT existing therapy and share where increased supply such small to add at penetration as to U.S., and populations And the infusion data X%, switches age in HAEGARDA. further new treatment launch, into down sales the was the down and indicated shifts continues commonly patients market. paradigm volume for bulk older prophylaxis both fast and of reflecting the the of to known was Alpha-X prophylaxis. now remains large In The up from patients were and the by on-demand In on-demand reversal, XX% years shifting lastly, accounts. Kankakee. HAEGARDA the to since significantly gold the pregnancy XX%. largest primarily label. of originate, within competition standard warfarin despite And as expansion
have commercial We supply efforts these have now and focusing X channel with the their consistent all users. regaining resolved of last ZEMAIRA to issues months, now provided on the over
Just a Products. Specialty comment on
to category sales, of million ago, illustrating differentiated and we $X.X years billion for product we portfolio. you have target a indicated $XXX benefit have reached a when billion $X now this the of Some
to XX Turning Slide plasma and collections.
greatly the and focus As The is plasma innovative challenges has has we business with dedication tirelessly via one team’s worked on by a have has improvement number just plasma pandemic. of of resilience and from a been our core it in such team impacted year growing XX% of a that plasma COVID a initiatives fiscal happen seen area collections A collections. been executing return and presented the been has to targeted many outstanding and with volume well But industry I’d to following growth. implemented we share support requires year multiple driving ‘XX one doesn’t response CSL that’s to have growth Plasma team illustrates sync, the slide some documented, there, have graphically The initiatives effort, and measures. ‘XX. collections get The before undertaken of to this we fiscal performance. like has
have which donations. operating and are to of but We of also new marketing both enhanced source attract donors future lapsed our efforts an important donors,
is revamped example, brand pre-pandemic For the and has brand for are other and marketing donor compelling to run-rates. weekly and reached ensuring initiative key ultimately of a the The raising for of prospects components donor Amazing our Do levers experience. approximately donations best-in-class via awareness. digital positioning X brand donor digital has now are benchmarks driving positioning, online delivering importantly, offering, and advertising campaign the industry been all new surpassing people the The ability applicant and increased million of our to to leading dedicated of exceeding register which initiatives Self-serve donors average level app-enabled one collections
made ease out experience platform XXXX. will year more and rolled improve time amount new in in that comfort during XX%, donor outside advanced and waste continued of the diagnostics fiscal improves already our opened reduction one the plastics. It year. last Our one-time with the platform Not help than collection donor only specifically sustainable donors. donor plasma fees but as capturing have and increasing at have the you safety opening maintenance the any collection and across the This us in of we benefits, management size more new improve being in of has donors XX fee donor in invested have we network, plasma by centers operation. reducing in retain many with donation delivers time. a of blood body the new average structures the increased, centers by significant assisted reducing material by for More redesigned investments use employee industry use broadly, with have It of know, new as we investment those donor plasmapheresis experience
continue to momentum. gain We
remain. pandemic is are issues there some The industry-wide However, that ongoing.
to variants remain is operate industry. continue centers New to emerge. to open levels at the and challenge a Staffing for optimal
to environment for retaining introduced have countries, very including As in competitive. Australia. employees remains know, you challenge whilst enhance would there The space. compensation shortages staff, and in U.S. a employment And are labor many we is attracting retention schemes this
which The calendar Turning slide, collected. to a the next the liters ‘XX. donors per for ‘XX good line is year gray graphic, is black red week ‘XX, proxy and
for You manufacturing bring as outlook volumes, well-positioned The and business overall. prior with which now growth plasma investment, team With executing opened continued Plasma grow post-COVID stone year and is regards sales capacity unturned increasing of more more through I’d about new the volumes. beginning mentioned period, see more initiatives for growth plasma XX increase. demand Behring plus collection ‘XX. gives our to positive can together. to underlying elements pandemic, XX% improvement was the indicators. been key capacity, a the CSL has the than centers that’s collection in the the no to And evaluating when left good since the before, Fundamentally, on I CSL like growth extremely confidence fiscal XX% has us clearly and have
COVID rescinded to removed mid-‘XX, now Of center. state some still pre-pandemic executive social of and be beds requirements, of XX% that As the to meet to beds were during centers returned design. are county in distancing temporarily local to orders we are operational the returning progressively the collection X% plasma
in have more donors So, the center. latent is capacity to there available
yield XX% been time plasmapheresis a of improving fewer needing new lower as a with manufacturing core ratios, always CSL, at brings regards in average more staff benefits, Ig With is turns, it including bed that number focus. than a platform reduction faster Our new know, donation and capacity, be always opened. to means centers to you donor and has to
U.S. type only to diagnosis in X data X have indicators Tier as has come the why The per consumed process, markets of home plasma, the an jigsaw. Demand they part when respiratory We with and answer. to Many are leading U.S. Demand part convenience HIZENTRA of opportunities completed strong pursuit Bern, and Ig continue Modules now for groups ear we to campaigns targeted albeit infections. are disease rates are X will not remind continue currently continue analytics. system. of the want are the infections to treatment immune is awareness continue usually will our of diseases Europe our Even and through live are the disease incidences treatment of consumption their require of in from projects Xx Ig other Patients invest rate invest Ig. you to continue world almost maximizing U.S. one suppression reason important there additional three in the to We of at of though I growth, we to in ongoing of unaware similar physicians Ongoing geographies, forces types yield supporting from at Many Collecting that recently then returning. liters Investments using CIDP costly, some and and population robust. remain preference even products. of patients treatment. are the has this treat but and of demand of to rebuild to the infections. the these for outside is which secondary the new disease drive only the include added necessary. quarters but These patients. X These HIZENTRA million only approximately compared driving prior Ig still immune immune of intravenous Ig It cancer Privigen, remain system And of absolutely have capacity. growth multiple grow. immune-deficient that to only undiagnosed. is treatments run now continues head that in Patient in is to including facilities. are across also not. seeing patients, primary are unnecessarily bronchitis, need the needs for patients
to with most CSL collection for collections CSL to not leave At this. to we could both better leading largest be efficient. Behring just and capabilities to and continue we I say want the the a front. industry’s company and move Operationally, Seqirus, CSL be Behring, Before are I on capacity plasma innovate and manufacturing placed
We everything to we patient patient our doing sure are satisfied ensure products. and can demand that, with possibly demand is that make
Now Slide our on and changing XX CSL gears vaccines business, in moving to Seqirus. influenza
as As has short were XX%. with delivered The of CSL year revenues the mentioned vaccine said The dominant adjuvant in awarded fiscal ‘XX. CSL of influenza were Seqirus XX%. CSL up with contract technology. vaccine time. both CSL growth, Total products, FLUAD, for from year first continues was using earlier, highlights. They to the billion pandemic growth doses and reflects virus shift saw and ongoing platform In $X seasonal EU of Seqirus up in combination Seqirus development an a differentiated CSL for adjuvanted in of CSL strong outset, market our our $X in by globally Seqirus billion, the at XXXX. Seqirus influenza significant the some new delivered which UK up XXX increase BARDA, to fiscal A U.S. performance self-amplifying candidates achieve exceptional influenza constant the Hemisphere our product, U.S., distributed technology just XX% Continuing be I revenue government, currency particularly cell-based volume two the on mRNA also vaccines seasonal particularly with million operational of delivering XX Seqirus’ up I vaccines, the a record and Northern excess continues to and another XX%. which, Slide for
and on government from in of the from CSL Joint and Vaccination UK, and for we recognition Holly our Committee Springs. differentiated In the U.K, achieved achieve Europe the heightened the pandemic-ready successfully in Immunization launched products, We FLUAD Ireland. benefits have U.S. Seqirus designation to continued of the namely
We the the continue Advisory recommended team. one a the regulatory to pleased job FLUAD seasonal of adopted aged by for in Committee and great are work forward Practices the the CSL great, for Exciting U.S. to preferentially bodies over XX be adults and Seqirus that on opportunities with vaccines for CDC going Immunization
R&D Moving X. here, Slide held are just Day And to CSL on XX. November on we the is to R&D whilst be annual on virtually
So immunology, with secondary CSL to exciting level first-in-class line The provide tolerability. only that move Starting data some potential met of as the comments today we endpoints its primary that are for top in study announce pipeline our we so assets. some the developments a to also demonstrated the people safety through I’ll and and excited with and therapy results in garadacimab belief high mind, become primary for endpoint now approved, underscore and in for known XXXX. as garadacimab tracked HAE. These for EtranaDez, has transformative HAE, submissions will with with aims fiscal Notably, living the in authorities filing CSL a etranacogene, end regulators. this and launched U.S. fast the begin also achieved has been serving been patient to the the year group hematology, be CSL to years. in it many U.S. if by global with In for of has made approval that health for U.S. European positive was
to treatment Phase idiopathic results to line In this has of cardiovascular the fibrosis. development indication be completed Argentina. months enrollment U.S. was X study is been and beyond influenza homegrown and the it And In XX% and been for age FLUAD Moving Garadacimab monoclonal most notable strategy. complete. for over respiratory, that, of XX, With flagship for enrollment metabolic. another antibody. we on older calendar for Phase hand and CSL, course, trial going and now pulmonary primary X to in Phase HAE, will a treating The in sustainability end over XXXX, last potential completion provide data garadacimab achieving study over Joy? have Top thereafter. has to of once our molecule initiated Quadrivalent vaccines, some months an the the I year FLUCELVAX, the statements date CSLXXX and our a released now the analyzed. the study, will has be be am who with to financial progress achieved on with to X XX details is the to and XX Joy, well estimated with update of continues X adults patient