and morning, Good in families are safe. you health your today. Thanks, for hope thank and us staying everyone good you I joining Ronnie. and
our market growth guidance, third increase the COVID-XX. solid with remain delivered innovative a strong quarter recovery results both recovery as impacts revenue expenses of for resilient sequential are Our in quarter virtual was pleased for the Total in an We through third managing by were quarter the the the and operations we the receptivity profit ongoing to financial out-of-pocket outperformance for in due in across and below reimbursable our solutions. slower driven slower in revenue segments, patient integrated was enrollment. which solely with
expectations reimbursable expenses, of reimbursable in of impact strong to line Commercial Solutions' the and the contributing a I'm pleased quarter, adjusted the was was the margin. in our expectations performance driven Excluding strength our of which margins with lower EBITDA revenue for Clinical Solutions' with revenue by during mix our the exceeded our partially expenses. quarter,
updated margin pattern the We expect reflected and over could we provide believe shift benefit in guidance, this to that a continue as structural long-term. this our
We strategy remain robust long-term continue to and differentiated the and backlog our confident given of our strength in on deliver our business, model.
capabilities strength extending technologies commitment to acquire dynamics areas, of our emerging expertise Syneos industry-leading trials our on scale the strong Further this looking we belief increase CRO broad combined We overlap. Health emerging to III, and is on a including and to disease, completed, business deploying of our growth well-regarded If welcoming ideally to believe we One mid-sized lead and Phase accelerate the COVID-XX brand. announced scale Synteract retain the customer space, their where look excellence, around companies. cement market biopharmaceutical create is philosophy II to segments within our in patient an will would leading growth, already conversion last and team in continue opportunity unit to global our Synteract's larger changing an the lives the pipelines. operational therapeutic focus of to small- their specialty improving CNS using our end-to-end synergies, full-service of our These Synteract. in in for to growth suited mid-sized, pediatrics, new favorable sector, segment biopharma support emerging acquisition in including right leveraging in to funding This Synteract oncology, dermatology, given to increases Synteract biotech Syneos performance. based is recovery. limited capabilities, win next forward night shares into position rare this and despite the agreement focused recent Health XXXX, pace their of expect strong family. revenue and aligned slowing amplifying in shared of both biopharma cases have the our we a Phase capture an to our offerings. ongoing strength forward and Syneos We're management rapid cultural chapter to and experiencing consulting ability the
independent have them we the possible of employees fuel around XX,XXX work for employees this our I the to innovation while to customer industry. recent among success each for selection to with continue our highlighted thank world, highest want of award the This throughout receiving every XXXX organizations outsourcing Employer as also recognition one Best we become. the culture collaborative for list. the would Additionally, launch polling on without company ranked based engagement capability, of Forbes contributing our biopharmaceutical by We our the Kinetic and and of been not to have
Now I'll quarter. key turn the to highlights from
period. organization. closed of our Clinical resulting growth First, times in us XX-month trailing times X.X book-to-bill aggregate awards, including and net times for QX of of This Commercial net Solutions' times Clinical of for awards Solutions, the billion an and business brings we ratio $X.X new for XX.X%, X.XX Solutions X.XX solid year-over-year ratios for book-to-bill total to with X.X
the business, For this year-over-year growth backlog XX-month growth improving revenue our period for accelerating to in Clinical strong trailing a growth builds for XX.X% position net awards with and XX.X%.
our of availability increase strong credit during adjusted third, revolving to We the strengthening margin flow $XXX.X robust position $XXX.X facility the for of point experienced and $XXX leverage liquidity. we and profitability with And we million XX.X%. quarter with X.X% basis net further million quarter times. year-over-year our period, generated million overall third growth unrestricted on Secondly, the with operating financial of cash and EBITDA X.X cash ended the of XXX
getting sequential a the third excluding quarter, Now staffing of recovery during We the saw revenue results. second to details strong second with the divestiture of quarter into business. compared of total quarter, our contingent our growth X.X% the
operations when customers, revenue quarter, the over staffing progressive during closely growing continue Clinical teams Clinical investigative a the showed Solutions HCPs balance delivered sequential with with of back growing awards, Gross Our to in customer to remain a contingent small recovery compared transition year. our remote face-to-face to work XX.X% a of quarter of Solutions' quarter awards operations. and solid strongest also awards sites XX.X% third the strong, normalizing divestiture record business. the mid-sized second quarter including segment. for last net our to to very
Our reflecting a backlog were net expenses. expectations awards impacted our changes by in adjustment, for reimbursable
pandemic, the billion ongoing period, net visits. increasing remote This the our coupled our ratio same X.X mix an with for increased period $X.X to in we awards Clinical the of As the operations of XX-month to times. for global expenses these an by anticipate site network, trailing the brings book-to-bill remote legacy lower ongoing operations centralization costs, in travel of driven reduction and
double-digit in quarter. third Our including year-to-date, growth SMID a RFP Clinical record flow pipeline remains fueled segments, robust by across customer
have through for end awards burn a much are QX. won COVID XX existing backlog. with of clinical We the profile projects treatments COVID-related of similar also to These approximately our primarily
than rapid vaccine more that awards, burn profile experienced at end anticipated activity a of we will of COVID-XX. have XX% an the a backlog no secure a represents substantial early meaningful expenses, year-to-date cancellation large-scale Although pipeline less did gross study of as see consequence opportunities. start our adjustment, in COVID-related QX, This of have continue we with the reimbursable additional for and we out-of-pocket a to of Outside XXXX.
for the operational quarter, our they outperformed of had patient our programs strong that have of was vote see expected XXXX. net stage compared growth COVID However, to the quarter a XX-month with Solutions therapies, resurgence backlog best expected and awards XX,XXX XXXX. our high solid period, we XX team than adapting Commercial our Since approximately to Solutions compared also by Commercial believe resulted CRO I billion expectations two enrollment Commercial seamlessly achievement to utilization monitoring quarter growth This created Solutions original recovery. be received expectations $X.X for in across of top with remote of the a recently Commercial also commitment for our cases. studies awards Award end sequential was to to for drove XX sites and by performance the partnership. which industry a This deliver our the relationships. launch We're Eagle X.X%. of quarter, investigative integrated ratio approved third continue times. slower X.XX are also to maintaining customers. a virtual both honored Syneos COVID-XX of resulting third of in across delays the recognizing in trailing total book-to-bill in of Health face-to-face has customer settings continue their the for the of this a notable site fourth for pharma employees to revenue in of X% that and the our awarded applaud countries site consecutive are demonstrates year, selected leadership nearly sites to
evaluate customers light demand timing strategies metrics and update our growth remains broader highlighted of demonstrating me pace the growth, approvals. their provide will operating of in Solutions robust, strategies let pipeline robust by some recent we COVID-XX. the evolving pipeline recovering of even on complexity growing Commercial backlog as customer and of remain market, us and product With macro environment fueled an of position in in Our have XXXX to Commercial key context, We in the beyond, that the product FDA-neutral confident that months. strong rapid the the
level sites, continued teams sites clinical physical improvement with of of to in about Our now access their some XX% visits. investigative steady permitting to physical see
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least While cautious end. amid around to continue still in to year expect we by our at generally of localized COVID-XX XX% somewhat degree some increases to be physically sites sites accessible be cases,
customers adoption reimbursable the increased visits into lower terms levels possible. visit continued where expect These and our a in to also dynamics both be should growth to the higher offset to our of site percentage margin. in fourth XXXX, more of supporting by efficiency compared revenue and remote sites future activity, a of EBITDA accelerated visits pre-COVID-XX expenses and expansion somewhat as technologies, have of create efficient reduced monitoring of adjusted quarter evolving This their headwind revenue. We remote our represent
enrollment levels. patient are patient both teams also new at recovered the and new are level and improvement in during clinical the of to of Our pre-COVID continued levels trending enrollment The XXX% of activations XX% pre-COVID site new trials. starts experiencing has of pace October, clinical about
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permitted large customer, by Our physical of and XX% territories. their the pharma divestiture again omnichannel of visits the visits of FSP levels are now our expect staffing on to The remained return resilient, this of currently Clinical approximately varies into customers return as year-over-year a Commercial strategy reimbursable Within HCP pace We in-person visits areas. with growth, impact customers these to by experiencing the COVID excluding XX% our their field in gradual revenue taking to back stance continued and teams on some allowing field our teams in a business. business increased have to our Deployment of certain teams of conduct have be Solutions' about contingent Solutions, cautious their experiencing for to has physical execute year-end. expenses
be analytics However, given for believe therapeutic interactions, teams certain approaches the no virtual required historical of our areas success to branded as promotional HCP expertise is agility effective. now science our leading fully advanced we that is by capability and deployment to we advanced technology field longer Kinetic, behavioral in XXX% further our and access that that combines physical data, omnichannel our This engagement. have optimize
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