Spruce Biosciences (SPRB)

Cash burn rate (est.)	Burn method: Change in cash		Burn method: Operating income		Burn method: FCF (opex + capex)
	Last Q	Avg 4Q	Last Q	Avg 4Q	Last Q	Avg 4Q
Cash on hand (at last report)	60.09 mm	60.09 mm	60.09 mm	60.09 mm		60.09 mm
Cash burn (monthly)	7.03 mm	3.12 mm	3.14 mm	3.91 mm		3.20 mm
Cash used (since last report)	19.81 mm	8.78 mm	8.83 mm	11.00 mm		9.02 mm
Cash remaining	40.28 mm	51.31 mm	51.26 mm	49.09 mm		51.07 mm
Runway (months of cash)	5.7	16.5	16.3	12.6		15.9

Beta Read what these cash burn values mean

Financial data from company earnings reports.

Institutional ownership, Q2 2024

SPRB institutional ownership history Ownership history

53.8% owned by funds/institutions

13F holders	Current	Prev Q	Change
Total holders	27	50	-46.0%
Opened positions	7	22	-68.2%
Closed positions	30	14	+114.3%
Increased positions	0	9	EXIT
Reduced positions	8	5	+60.0%

13F shares	Current	Prev Q	Change
Total value	4.72 bn	13.08 bn	-63.9%
Total shares	21.90 mm	32.03 mm	-31.6%
Total puts	59.30 k	24.90 k	+138.2%
Total calls	26.90 k	39.10 k	-31.2%
Total put/call ratio	2.2	0.6	+246.2%

Largest owners	Shares	Value	Change
5AM Opportunities II	4.14 mm	$10.63 mm	0.0%
HealthCap VIII	3.69 mm	$11.68 mm	0.0%
RiverVest Venture Management	2.94 mm	$1.52 bn	0.0%
Rock Springs Capital Management	2.61 mm	$1.35 bn	0.0%
Omega Fund VI	2.16 mm	$52.53 mm	0.0%
RiverVest Venture Fund III	1.80 mm	$4.52 mm	0.0%
Rosalind Advisors	1.51 mm	$780.91 mm	0.0%
Steve Elms	1.21 mm	$29.31 mm	0.0%
Altium Capital Management	811.17 k	$419.94 mm	-29.5%
Almitas Capital	396.51 k	$205.27 mm	NEW

Largest transactions	Shares	Bought/sold	Change
CG The Carlyle Group Inc.	0.00	-2.90 mm	EXIT
Novo Holdings A/S	0.00	-1.66 mm	EXIT
Aisling Capital Management	0.00	-1.21 mm	EXIT
Vanguard	0.00	-863.38 k	EXIT
Sands Capital Ventures	0.00	-787.01 k	EXIT
Almitas Capital	396.51 k	+396.51 k	NEW
Acadian Asset Management	0.00	-368.83 k	EXIT
ADAR1 Capital Management	0.00	-365.22 k	EXIT
Superstring Capital Management	77.99 k	-362.23 k	-82.3%
Altium Capital Management	811.17 k	-338.83 k	-29.5%

Data from 13F filings, for the last complete 13F reporting period. For most recent data, click the ownership history button. Values as filed, not updated for current price. Long positions only.

Recent insider trades

SPRB insider ownership history Insider history

Date	Owner	Security	Transaction	Code	Indirect	10b5-1	$Price	#Shares	$Value	#Remaining
16 Dec 24	Javier B. Szwarcberg	Common Stock	Payment of exercise	Dispose F	No	No	0.3887	39,605	15.39 k	467,191
16 Dec 24	Javier B. Szwarcberg	Common Stock	Option exercise	Acquire M	No	No	0	111,000	0.00	506,796
16 Dec 24	Javier B. Szwarcberg	Common Stock	Payment of exercise	Dispose F	No	No	0.3887	32,005	12.44 k	395,796
16 Dec 24	Javier B. Szwarcberg	Common Stock	Option exercise	Acquire M	No	No	0	89,700	0.00	427,801
16 Dec 24	Javier B. Szwarcberg	RSU Common Stock	Option exercise	Dispose M	No	No	0	111,000	0.00	222,000
16 Dec 24	Javier B. Szwarcberg	RSU Common Stock	Option exercise	Dispose M	No	No	0	89,700	0.00	269,100
16 Dec 24	Samir M. Gharib	Common Stock	Payment of exercise	Dispose F	No	No	0.3887	13,291	5.17 k	350,550
16 Dec 24	Samir M. Gharib	Common Stock	Option exercise	Acquire M	No	No	0	37,250	0.00	363,841
16 Dec 24	Samir M. Gharib	Common Stock	Payment of exercise	Dispose F	No	No	0.3887	13,737	5.34 k	326,591
16 Dec 24	Samir M. Gharib	Common Stock	Option exercise	Acquire M	No	No	0	38,500	0.00	340,328