Inovio Pharmaceuticals (INO) S-8Registration of securities for employees

In accordance with Rule 416 under the Securities Act of 1933, as amended, this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended. The price per share and aggregate offering price are calculated on the basis of $1.93, the average of the high and low price of the registrant’s Common Stock as reported on the Nasdaq Global Select Market on June 24, 2022.

The Registrant does not have any fee offsets.