| Cover | Oct. 31, 2024 |
| Cover [Abstract] | |
| Document Type | 8-K |
| Amendment Flag | false |
| Document Period End Date | Oct. 31, 2024 |
| Entity File Number | 001-38418 |
| Entity Registrant Name | Cocrystal Pharma, Inc. |
| Entity Central Index Key | 0001412486 |
| Entity Tax Identification Number | 35-2528215 |
| Entity Incorporation, State or Country Code | DE |
| Entity Address, Address Line One | 19805 N. Creek Parkway |
| Entity Address, City or Town | Bothell |
| Entity Address, State or Province | WA |
| Entity Address, Postal Zip Code | 98011 |
| City Area Code | (877) |
| Local Phone Number | 262-7123 |
| Written Communications | false |
| Soliciting Material | false |
| Pre-commencement Tender Offer | false |
| Pre-commencement Issuer Tender Offer | false |
| Title of 12(b) Security | Common Stock |
| Trading Symbol | COCP |
| Security Exchange Name | NASDAQ |
| Entity Emerging Growth Company | false |
