Exhibit 21
List Of Subsidiaries
The following is a list of subsidiaries of AbbVie Inc. as of December 31, 2021. AbbVie is not a subsidiary of any other corporation.
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| Domestic Subsidiaries | Incorporation |
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| AbbVie Aviation LLC | Illinois |
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| AbbVie Biopharmaceuticals LLC | Delaware |
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| AbbVie Bioresearch Center Inc. | Delaware |
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| AbbVie Biotech Ventures Inc. | Delaware |
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| AbbVie Biotherapeutics Inc. | Delaware |
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| AbbVie Domestic Holdings Inc. | Delaware |
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| AbbVie Endocrine Inc. | Delaware |
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| AbbVie Endocrinology Inc. (d/b/a Pharmacy Solutions) | Delaware |
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| AbbVie Finance Corporation | Delaware |
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| AbbVie Finance LLC | Delaware |
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| AbbVie Global Inc. | Delaware |
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| AbbVie Global Holdings Inc. | Delaware |
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| AbbVie Holdco Inc. | Delaware |
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| AbbVie Holdings Inc. | Delaware |
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| AbbVie International Inc. | Delaware |
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| AbbVie Investments Inc. | Delaware |
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| AbbVie Pharma Inc. | Delaware |
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| AbbVie Pharmaceuticals LLC | Delaware |
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| AbbVie Products LLC | Georgia |
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| AbbVie Purchasing LLC | Delaware |
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| AbbVie Resources Inc. | Delaware |
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| AbbVie Resources International Inc. | Delaware |
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| AbbVie Respiratory LLC | Delaware |
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| AbbVie Sales Inc. | Delaware |
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| AbbVie Services Inc. | Delaware |
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| AbbVie Stemcentrx LLC | Delaware |
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| AbbVie Subsidiary LLC | Delaware |
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| AbbVie US Holdings LLC | Delaware |
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| AbbVie US LLC | Delaware |
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| AbbVie Ventures LLC | Delaware |
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| Aeropharm Technology, LLC | Delaware |
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| AGN International Inc. | Delaware |
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| AGN Kythera, LP | Delaware |
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| AGN Labs LLC | Delaware |
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| AGN LLC | Delaware |
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| AGN Sundry, LLC | Delaware |
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| Allergan Akarna LLC | Delaware |
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| Allergan Finance, LLC | Nevada |
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| ALLERGAN FINCO 2 INC. | Delaware |
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| ALLERGAN FINCO INC. | Delaware |
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| Allergan GI Corp | Delaware |
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| Allergan GP Holding LLC | Delaware |
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| Allergan Holdco US, Inc. | Delaware |
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| Allergan Holdings B1, Inc. | Delaware |
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| Allergan Holdings, Inc. | Delaware |
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| Allergan, Inc. | Delaware |
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| Allergan Laboratories, LLC | Delaware |
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| Allergan Lending 2 LLC | Delaware |
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| Allergan Lending LLC | Delaware |
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| Allergan Pharma Inc. | Delaware |
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| Allergan Property Holdings, LLC | Delaware |
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| Allergan Puerto Rico Holdings, Inc. | Delaware |
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| Allergan Sales Puerto Rico, Inc. | California |
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| Allergan Sales, LLC (d/b/a Allergan; d/b/a Bioscience Laboratories) | Delaware |
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| Allergan Therapeutics LLC | Delaware |
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| Allergan USA, Inc. (d/b/a Pacificom / Pacific Communications) | Delaware |
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| Allergan W.C. Holding Inc. | Delaware |
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| Anterios, Inc. | Delaware |
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| Aptalis Pharma US, Inc. | Delaware |
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| AqueSys, Inc. | Delaware |
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| BioDisplay Technologies, Inc. | Illinois |
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| Bonti, Inc. | Delaware |
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| Cearna Aesthetics, Inc. | Delaware |
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| Chase Pharmaceuticals Corporation | Delaware |
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| Del Mar Indemnity Company LLC | Hawaii |
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| Durata Holdings, Inc. | Delaware |
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| Durata Therapeutics, Inc. | Delaware |
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| Durata Therapeutics U.S. Limited | Delaware |
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| Eden Biodesign, LLC | Delaware |
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| Envy Medical, Inc. | Delaware |
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| Exemplar Pharma, LLC | Delaware |
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| Foresight Vision5, Inc. | Delaware |
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| Fremont Holding L.L.C. | Delaware |
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| Furiex Pharmaceuticals LLC | Delaware |
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| IEP Pharmaceutical Devices, LLC | Delaware |
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| Keller Medical, Inc. | Delaware |
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| Knoll Pharmaceutical Company | New Jersey |
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| KOS Pharmaceuticals, Inc. | Delaware |
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| Life Properties Inc. | Delaware |
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| LifeCell Corporation | Delaware |
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| MAP Pharmaceuticals, LLC | Delaware |
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| Mavupharma, Inc. | Delaware |
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| MPEX Pharmaceuticals, Inc. | Delaware |
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| Naurex Inc. | Delaware |
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| Oculeve, Inc. | Delaware |
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| Organics L.L.C. | Delaware |
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| Pacific Pharma, Inc. | Delaware |
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| Pharmacyclics LLC | Delaware |
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| Pharmax Holding Limited | Delaware |
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| Repros Therapeutics Inc. | Delaware |
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| Rowell Laboratories, Inc. | Minnesota |
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| RP Merger Sub, Inc. | Delaware |
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| Sapphire Merger Sub, Inc. | Delaware |
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| Silicone Engineering, Inc. | California |
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| Soliton Inc. | Delaware |
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| Suffolk Merger Sub, Inc. | Delaware |
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| TeneoOne, Inc. | Delaware |
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| Tobira Therapeutics, Inc. | Delaware |
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| Topokine Therapeutics, Inc. | Delaware |
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| Transderm, Inc. | Delaware |
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| Unimed Pharmaceuticals, LLC | Delaware |
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| Venice Subsidiary LLC | Delaware |
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| Vicuron Pharmaceuticals LLC | Delaware |
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| Vitae Pharmaceuticals, LLC | Delaware |
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| Warner Chilcott Leasing Equipment Inc. | Delaware |
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| Warner Chilcott Sales (US), LLC | Delaware |
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| Zeltiq A LLC | Delaware |
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| Zeltiq Aesthetics, Inc. | Delaware |
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| Zeltiq International, LLC | Delaware |
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| Foreign Subsidiaries | Incorporation |
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| AbbVie S.A. | Argentina |
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| Allergan Productos Farmaceuticos S.A. | Argentina |
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| Allergan Australia Pty Limited | Australia |
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| Elastagen Pty Ltd | Australia |
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| Kythera Biopharmaceuticals Australia Pty Ltd | Australia |
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| AbbVie Pty Ltd | Australia |
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| AbbVie GmbH | Austria |
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| AbbVie Bahamas Ltd. | Bahamas |
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| AbbVie SA | Belgium |
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| Allergan N.V. | Belgium |
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| Odyssea Pharma SPRL | Belgium |
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| AbbVie Ltd | Bermuda |
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| AbbVie Biotechnology Ltd | Bermuda |
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| AbbVie Finance Limited | Bermuda |
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| AbbVie Global Enterprises Ltd. | Bermuda |
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| AbbVie Holdings Unlimited | Bermuda |
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| Allergan Development Ventures I, LP | Bermuda |
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| Allergan Holdings B Ltd. | Bermuda |
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| Allergan Holdings B2, Ltd. | Bermuda |
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| Kythera Holdings Ltd | Bermuda |
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| Warner Chilcott Holdings Company II, Limited | Bermuda |
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| Warner Chilcott Holdings Company III, Limited | Bermuda |
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| Warner Chilcott Limited | Bermuda |
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| AbbVie d.o.o. | Bosnia |
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| AbbVie Farmacêutica Ltda. | Brazil |
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| Allergan Productos Farmaceuticos Ltda. | Brazil |
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| AbbVie EOOD | Bulgaria |
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| Allergan Bulgaria EOOD | Bulgaria |
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| AbbVie Corporation | Canada |
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| AbbVie Holdings Corporation | Canada |
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| Allergan Inc. | Canada |
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| Aptalis Pharma Canada ULC | Canada (Alberta) |
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| Allergan Holdings C, Ltd. | Cayman Islands |
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| Allergan Overseas Holding | Cayman Islands |
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| Pharmacyclics Cayman Ltd. | Cayman Islands |
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| Stemcentrx Cayman Ltd. | Cayman Islands |
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| AbbVie Productos Farmacéuticos Limitada | Chile |
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| Allergan Laboratorios Limitada | Chile |
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| AbbVie Pharmaceutical Trading (Shanghai) Co., Ltd. | China |
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| Allergan (Chengdu) Medical Aesthetics Clinic Co., Ltd. | China |
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| Allergan Information Consulting (Shanghai) Co., Ltd. | China |
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| Allergan Medical Device (Shanghai) Co., Ltd. | China |
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| AbbVie S.A.S. | Colombia |
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| Allergan de Colombia S.A. | Colombia |
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| Allergan Costa Rica S.R.L. | Costa Rica |
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| AbbVie d.o.o. | Croatia |
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| AbbVie Limited | Cyprus |
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| AbbVie s.r.o. | Czech Republic |
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| Allergan CZ, s.r.o. | Czech Republic |
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| AbbVie A/S | Denmark |
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| Allergan ApS | Denmark |
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| AbbVie, S.R.L. | Dominican Republic |
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| AbbVie L.L.C. | Egypt |
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| AbbVie OÜ | Estonia |
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| AbbVie Oy | Finland |
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| Allergan Finland Oy | Finland |
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| AbbVie SAS | France |
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| Allergan France SAS | France |
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| Allergan Holdings France SAS | France |
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| Allergan Industrie SAS | France |
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| Eurand France S.A.S. | France |
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| Forest Holdings France S.A.S. | France |
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| AbbVie Biotechnology GmbH | Germany |
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| AbbVie Deutschland GmbH & Co. KG | Germany |
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| AbbVie Komplementär GmbH | Germany |
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| AbbVie Pharmaceuticals GmbH | Germany |
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| AbbVie Real Estate Management GmbH | Germany |
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| Allergan GmbH | Germany |
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| AbbVie (Gibraltar) Holdings Limited | Gibraltar |
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| AbbVie (Gibraltar) Limited | Gibraltar |
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| AbbVie Pharmaceuticals Societe Anonyme | Greece |
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| Allergan Hellas Pharmaceuticals S.A. | Greece |
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| AbbVie, Socieded Anonima | Guatemala |
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| AbbVie Limited | Hong Kong |
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| Allergan Hong Kong Limited | Hong Kong |
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| AbbVie Gyogyszerkereskedelmi Korlatolt Felelossegu Tarsasag | Hungary |
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| Allergan Hungary Kft. | Hungary |
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| Allergan Healthcare India Private Limited | India |
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| Allergan India Private Limited* | India |
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| AbbVie International Holdings Unlimited Company | Ireland |
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| AbbVie Ireland Holdings Unlimited Company | Ireland |
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| AbbVie Ireland Unlimited Company | Ireland |
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| AbbVie Limited | Ireland |
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| AbbVie Manufacturing Management Unlimited Company | Ireland |
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| Allergan Botox Unlimited Company (In voluntary liquidation) | Ireland |
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| Allergan Equities Unlimited Company | Ireland |
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| Allergan Furiex Ireland Limited (In voluntary liquidation) | Ireland |
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| Allergan Holdings Unlimited Company | Ireland |
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| Allergan Ireland Holdings Unlimited Company | Ireland |
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| Allergan Ireland Limited | Ireland |
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| Allergan Limited | Ireland |
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| Allergan Pharma Limited | Ireland |
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| Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company (In voluntary liquidation) | Ireland |
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| Allergan Pharmaceuticals International Limited | Ireland |
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| Allergan Pharmaceuticals Ireland Unlimited Company | Ireland |
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| Allergan Services International, Unlimited Company | Ireland |
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| Allergan WC Ireland Holdings Limited | Ireland |
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| Forest Laboratories Ireland Limited | Ireland |
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| Fournier Laboratories Ireland Limited | Ireland |
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| Pharmacyclics (Europe) Limited | Ireland |
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| Tosara Exports Limited (In voluntary liquidation) | Ireland |
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| Warner Chilcott Intermediate (Ireland) ULC | Ireland |
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| Zeltiq Ireland International Holdings Unlimited Company | Ireland |
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| Zeltiq Ireland Unlimited Company | Ireland |
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| AbbVie Biopharmaceuticals Ltd. | Israel |
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| Allergan Israel Ltd. | Israel |
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| Marbelle Threads Ltd. | Israel |
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| AbbVie S.r.l. | Italy |
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| Allergan S.p.A. | Italy |
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| Aptalis Pharma S.r.l. | Italy |
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| AbbVie GK | Japan |
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| Allergan International YK | Japan |
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| Allergan Japan KK | Japan |
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| Allergan K.K. | Japan |
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| Allergan NK | Japan |
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| AbbVie Ltd | Korea, South |
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| Allergan Korea Ltd. | Korea, South |
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| AbbVie SIA | Latvia |
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| AbbVie UAB | Lithuania |
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| Allergan Baltics, UAB | Lithuania |
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| AbbVie Biotherapeutics S.àr.l. | Luxembourg |
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| AbbVie Holdings S.à r.l. | Luxembourg |
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| AbbVie Global S.à r.l. | Luxembourg |
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| Allergan AHI S.à r.l. | Luxembourg |
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| Allergan Capital 2 S.à r.l. | Luxembourg |
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| Allergan Capital S.à r.l. | Luxembourg |
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| Allergan Europe S.à r.l. | Luxembourg |
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| Allergan Finance S.à r.l. | Luxembourg |
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| Allergan Funding SCS | Luxembourg |
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| Allergan Global S.à r.l. | Luxembourg |
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| Allergan Holdings S.à r.l. | Luxembourg |
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| Allergan International Holding S.à r.l. | Luxembourg |
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| Allergan Luxembourg International S.à r.l. | Luxembourg |
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| Allergan WC 1 S.à r.l. | Luxembourg |
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| Allergan WC 2 S.à r.l. | Luxembourg |
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| AbbVie Sdn. Bhd. | Malaysia |
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| Allergan Malaysia Sdn Bhd | Malaysia |
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| Allergan Malta Holding Limited | Malta |
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| Allergan Malta II Limited | Malta |
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| Allergan Malta Limited | Malta |
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| AbbVie Farmacéuticos, S.A. de C.V. | Mexico |
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| Allergan Servicios Profesionales, S. de R.L. de C.V. | Mexico |
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| Allergan, S.A. de C.V. | Mexico |
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| AbbVie B.V. | Netherlands |
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| AbbVie Central Finance B.V. | Netherlands |
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| AbbVie Enterprises B.V. | Netherlands |
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| AbbVie Finance B.V. | Netherlands |
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| AbbVie Ireland NL B.V. | Netherlands |
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| AbbVie Japan Holdings B.V. | Netherlands |
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| AbbVie Logistics B.V. | Netherlands |
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| AbbVie Nederland Holdings B.V. | Netherlands |
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| AbbVie Pharmaceuticals B.V. | Netherlands |
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| AbbVie Research B.V. | Netherlands |
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| AbbVie Venezuela B.V. | Netherlands |
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| AbbVie Venezuela Holdings B.V. | Netherlands |
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| Allergan B.V. | Netherlands |
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| Aptalis Holding B.V. | Netherlands |
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| Aptalis Netherlands B.V. | Netherlands |
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| Forest Finance B.V. | Netherlands |
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| Warner Chilcott Nederland B.V. | Netherlands |
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| AbbVie Limited | New Zealand |
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| Allergan New Zealand Limited | New Zealand |
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| AbbVie AS | Norway |
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| Allergan AS | Norway |
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| AbbVie, S. de R.L. | Panama |
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| Allergan Healthcare Philippines, Inc. | Philippines |
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| AbbVie Polska Sp. z o.o. | Poland |
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| AbbVie Sp. z o.o. | Poland |
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| Allergan Sp. z o.o. | Poland |
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| AbbVie, L.da | Portugal |
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| AbbVie Promoção, L.da | Portugal |
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| AbbVie Corp | Puerto Rico |
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| Knoll LLC | Puerto Rico |
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| AbbVie S.R.L. | Romania |
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| AbbVie Trading S.R.L. | Romania |
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| Allergan S.R.L. | Romania |
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| AbbVie Limited Liability Company | Russia |
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| Allergan C.I.S. S.a.r.l. | Russia |
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| Allergan Saudi Arabia LLC* | Saudi Arabia |
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| Allergan d.o.o. Beograd | Serbia |
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| AbbVie Operations Singapore Pte. Ltd. | Singapore |
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| AbbVie Pte. Ltd. | Singapore |
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| Allergan Singapore Pte. Ltd. | Singapore |
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| AbbVie Holdings s.r.o. | Slovakia |
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| AbbVie s.r.o. | Slovakia |
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| Allergan SK s.r.o. | Slovakia |
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| AbbVie Biofarmacevtska druzba d.o.o. | Slovenia |
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| AbbVie (Pty) Ltd. | South Africa |
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| Allergan Pharmaceuticals (Proprietary) Limited | South Africa |
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| AbbVie Spain, S.L. | Spain |
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| Allergan S.A. | Spain |
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| AbbVie AB | Sweden |
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| Allergan Norden AB | Sweden |
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| AbbVie AG | Switzerland |
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| AbbVie Biopharmaceuticals GmbH | Switzerland |
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| Allergan AG | Switzerland |
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| Pharmacyclics Switzerland GmbH | Switzerland |
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| VarioRaw Percutive S.à r.l. | Switzerland |
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| Warner Chilcott Pharmaceuticals S à rl | Switzerland |
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| Allergan Pharmaceuticals Taiwan Co. Ltd. | Taiwan |
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| AbbVie Ltd. | Thailand |
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| Allergan (Thailand) Limited | Thailand |
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| AbbVie Sarl | Tunisia |
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| AbbVie Tıbbi İlaçlar Sanayi ve Ticaret Limited Şirketi | Turkey |
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| Allergan Ilaclari Ticaret Anonim Sirketi | Turkey |
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| Allergan Ukraine LLC | Ukraine |
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| Allergan Middle East Limited | United Arab Emirates |
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| AbbVie Australasia Holdings Limited | United Kingdom |
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| AbbVie Biotherapeutics Limited | United Kingdom |
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| AbbVie Investments Limited | United Kingdom |
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| AbbVie Ltd | United Kingdom |
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| AbbVie Trustee Company Limited | United Kingdom |
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| AbbVie UK Holdco Limited | United Kingdom |
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| Akarna Therapeutics, Limited | United Kingdom |
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| Allergan Holdco UK Limited | United Kingdom |
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| Allergan Holdings Limited | United Kingdom |
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| Allergan Limited | United Kingdom |
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| Lifecell EMEA Limited (In voluntary liquidation) | United Kingdom |
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| Renable Pharma Ltd. | United Kingdom |
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| Zeltiq Limited (In voluntary liquidation) | United Kingdom |
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| AbbVie S.A. | Uruguay |
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| AbbVie Pharmaceuticals SCA. | Venezuela |
* Ownership of such subsidiary is less than 100% by AbbVie or an AbbVie subsidiary
