Rock Springs Capital Management 13FHR Quarterly holdings report by institutional manager | SEC 15 May 24

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	93,281,550	1,177,500	SH		SOLE		1,177,500	0	0
ACCOLADE INC	COM	00437E102	37,099,200	3,540,000	SH		SOLE		3,540,000	0	0
ACLARIS THERAPEUTICS INC	COM	00461U105	3,414,334	2,753,495	SH		SOLE		2,753,495	0	0
ACUMEN PHARMACEUTICALS INC	COM	00509G209	9,315,239	2,300,059	SH		SOLE		2,300,059	0	0
ADAPTIMMUNE THERAPEUTICS PLC	SPONDS ADR	00653A107	3,832,239	2,425,468	SH		SOLE		2,425,468	0	0
AGILON HEALTH INC	COM	00857U107	53,893,500	8,835,000	SH		SOLE		8,835,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	51,594,126	1,764,505	SH		SOLE		1,764,505	0	0
AKERO THERAPEUTICS INC	COM	00973Y108	32,835,171	1,299,888	SH		SOLE		1,299,888	0	0
ALIGN TECHNOLOGY INC	COM	016255101	72,142,400	220,000	SH		SOLE		220,000	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	4,857,125	32,500	SH	Call	SOLE		32,500	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	36,465,800	244,000	SH		SOLE		244,000	0	0
AMICUS THERAPEUTICS INC	COM	03152W109	13,578,288	1,152,656	SH		SOLE		1,152,656	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	2,872,410	1,011,412	SH		SOLE		1,011,412	0	0
APPLIED THERAPEUTICS INC	COM	03828A101	10,185,842	1,497,918	SH		SOLE		1,497,918	0	0
ARGENX SE	SPONSORED ADR	04016X101	90,260,310	229,250	SH		SOLE		229,250	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	43,839,300	290,000	SH		SOLE		290,000	0	0
AURINIA PHARMACEUTICALS INC	COM	05156V102	5,763,238	1,150,347	SH		SOLE		1,150,347	0	0
AUTOLUS THERAPEUTICS PLC	SPON ADS	05280R100	6,590,463	1,032,988	SH		SOLE		1,032,988	0	0
AZENTA INC	COM	114340102	41,879,530	694,750	SH		SOLE		694,750	0	0
BEAM THERAPEUTICS INC	COM	07373V105	4,873,730	147,510	SH		SOLE		147,510	0	0
BIOCRYST PHARMACEUTICALS INC	COM	09058V103	17,760,980	3,496,256	SH		SOLE		3,496,256	0	0
BIOHAVEN LTD	COM	G1110E107	6,944,755	126,984	SH		SOLE		126,984	0	0
BIOMARIN PHARMACEUTICAL INC	COM	09061G101	12,998,987	148,832	SH		SOLE		148,832	0	0
BIOMEA FUSION INC	COM	09077A106	2,708,148	181,147	SH		SOLE		181,147	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	237,002,777	2,498,448	SH		SOLE		2,498,448	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	84,413,925	1,232,500	SH		SOLE		1,232,500	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	57,590,604	1,372,185	SH		SOLE		1,372,185	0	0
CEREVEL THERAPEUTICS HLDNG I	COM	15678U128	23,161,677	547,946	SH		SOLE		547,946	0	0
CG ONCOLOGY INC	COM	156944100	7,500,710	170,859	SH		SOLE		170,859	0	0
CHARLES RIV LABS INTL INC	COM	159864107	13,141,075	48,500	SH		SOLE		48,500	0	0
COLLEGIUM PHARMACEUTICAL INC	COM	19459J104	21,816,840	562,000	SH		SOLE		562,000	0	0
COMPASS THERAPEUTICS INC	COM	20454B104	10,917,300	5,513,788	SH		SOLE		5,513,788	0	0
COMPUGEN LTD	ORD	M25722105	3,328,174	1,289,990	SH		SOLE		1,289,990	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	13,546,814	289,400	SH		SOLE		289,400	0	0
DEXCOM INC	COM	252131107	82,769,225	596,750	SH		SOLE		596,750	0	0
DISC MEDICINE INC	COM	254604101	22,629,518	363,468	SH		SOLE		363,468	0	0
DYNAVAX TECHNOLOGIES CORP	COM NEW	268158201	20,792,632	1,675,474	SH		SOLE		1,675,474	0	0
DYNE THERAPEUTICS INC	COM	26818M108	12,827,283	451,824	SH		SOLE		451,824	0	0
EDAP TMS S A	SPONSORED ADR	268311107	10,841,250	1,475,000	SH		SOLE		1,475,000	0	0
EDWARDS LIFESCIENCES CORP	COM	28176E108	61,855,988	647,300	SH		SOLE		647,300	0	0
ELI LILLY & CO	COM	532457108	80,324,370	103,250	SH		SOLE		103,250	0	0
ENLIVEN THERAPEUTICS INC	COM	29337E102	7,538,564	428,571	SH		SOLE		428,571	0	0
ESSA PHARMA INC	COM NEW	29668H708	5,747,772	677,005	SH		SOLE		677,005	0	0
EVOLENT HEALTH INC	CL A	30050B101	130,750,125	3,987,500	SH		SOLE		3,987,500	0	0
EXACT SCIENCES CORP	COM	30063P105	73,186,335	1,059,750	SH		SOLE		1,059,750	0	0
FRESHPET INC	COM	358039105	76,757,250	662,500	SH		SOLE		662,500	0	0
FULCRUM THERAPEUTICS INC	COM	359616109	6,869,233	727,673	SH		SOLE		727,673	0	0
GOSSAMER BIO INC	COM	38341P102	3,855,013	3,266,960	SH		SOLE		3,266,960	0	0
GOSSAMER BIO INC	NOTE 5.000% 6/0	38341PAA0	3,844,670	9,573,000	PRN		SOLE		9,573,000	0	0
HUMANA INC	COM	444859102	51,109,302	147,408	SH		SOLE		147,408	0	0
IDEXX LABS INC	COM	45168D104	96,782,453	179,250	SH		SOLE		179,250	0	0
IMMATICS N.V	SHS	N44445109	8,920,373	848,751	SH		SOLE		848,751	0	0
IMMUNOCORE HLDGS PLC	ADS	45258D105	153,908,040	2,367,816	SH		SOLE		2,367,816	0	0
IMMUNOVANT INC	COM	45258J102	37,160,474	1,150,123	SH		SOLE		1,150,123	0	0
INOZYME PHARMA INC	COM	45790W108	28,197,793	3,681,174	SH		SOLE		3,681,174	0	0
INSPIRE MED SYS INC	COM	457730109	28,030,095	130,500	SH		SOLE		130,500	0	0
INSULET CORP	COM	45784P101	54,848,000	320,000	SH		SOLE		320,000	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	119,128,365	298,500	SH		SOLE		298,500	0	0
IRHYTHM TECHNOLOGIES INC	COM	450056106	45,501,000	392,250	SH		SOLE		392,250	0	0
JASPER THERAPEUTICS INC	COM NEW	471871202	11,871,276	404,335	SH		SOLE		404,335	0	0
KRYSTAL BIOTECH INC	COM	501147102	18,499,204	103,969	SH		SOLE		103,969	0	0
KYMERA THERAPEUTICS INC	COM	501575104	61,193,968	1,522,238	SH		SOLE		1,522,238	0	0
KYVERNA THERAPEUTICS INC	COM	501976104	4,445,441	178,963	SH		SOLE		178,963	0	0
LEAP THERAPEUTICS INC	COM NEW	52187K200	2,425,752	911,937	SH		SOLE		911,937	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	28,016,170	499,486	SH		SOLE		499,486	0	0
LIFESTANCE HEALTH GROUP INC	COM	53228F101	29,492,600	4,780,000	SH		SOLE		4,780,000	0	0
MACROGENICS INC	COM	556099109	19,213,280	1,305,250	SH		SOLE		1,305,250	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	76,355,014	285,931	SH		SOLE		285,931	0	0
MEREO BIOPHARMA GROUP PLC	SPON ADS	589492107	26,868,960	8,142,109	SH		SOLE		8,142,109	0	0
MERSANA THERAPEUTICS INC	COM	59045L106	13,649,583	3,046,782	SH		SOLE		3,046,782	0	0
MERUS N V	COM	N5749R100	51,629,597	1,146,560	SH		SOLE		1,146,560	0	0
MINERALYS THERAPEUTICS INC	COM	603170101	10,232,660	792,615	SH		SOLE		792,615	0	0
MIRUM PHARMACEUTICALS INC	COM	604749101	46,636,888	1,856,564	SH		SOLE		1,856,564	0	0
NEUMORA THERAPEUTICS INC.	COM	640979100	8,884,123	646,118	SH		SOLE		646,118	0	0
NEUROCRINE BIOSCIENCES INC	NOTE 2.250% 5/1	64125CAD1	1,807,250	1,000,000	PRN		SOLE		1,000,000	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	145,491,808	1,054,900	SH		SOLE		1,054,900	0	0
NEVRO CORP	NOTE 2.750% 4/0	64157FAC7	473,869	500,000	PRN		SOLE		500,000	0	0
NEVRO CORP	COM	64157F103	15,378,600	1,065,000	SH		SOLE		1,065,000	0	0
NOVAVAX INC	COM NEW	670002401	2,569,848	537,625	SH		SOLE		537,625	0	0
NOVO-NORDISK A S	ADR	670100205	18,939,000	147,500	SH		SOLE		147,500	0	0
NUVALENT INC	COM	670703107	9,408,927	125,302	SH		SOLE		125,302	0	0
NUVATION BIO INC	*W EXP 07/07/202	67080N119	40,543	134,028	SH		SOLE		134,028	0	0
OLINK HLDG AB	SPONSORED ADS	680710100	39,414,515	1,676,500	SH		SOLE		1,676,500	0	0
OSCAR HEALTH INC	CL A	687793109	31,375,700	2,110,000	SH		SOLE		2,110,000	0	0
PACIRA BIOSCIENCES INC	COM	695127100	30,841,710	1,055,500	SH		SOLE		1,055,500	0	0
PENUMBRA INC	COM	70975L107	112,705,900	505,000	SH		SOLE		505,000	0	0
PHARVARIS N V	COM	N69605108	17,400,074	752,924	SH		SOLE		752,924	0	0
PHREESIA INC	COM	71944F106	56,594,450	2,365,000	SH		SOLE		2,365,000	0	0
PLIANT THERAPEUTICS INC	COM	729139105	5,736,440	384,996	SH		SOLE		384,996	0	0
PROTHENA CORP PLC	SHS	G72800108	15,482,439	625,048	SH		SOLE		625,048	0	0
PULMONX CORP	COM	745848101	6,047,748	652,400	SH		SOLE		652,400	0	0
RENEO PHARMACEUTICALS INC	COM	75974E103	1,247,872	751,730	SH		SOLE		751,730	0	0
REVOLUTION MEDICINES INC	COM	76155X100	29,770,239	923,681	SH		SOLE		923,681	0	0
RHYTHM PHARMACEUTICALS INC	COM	76243J105	65,986,954	1,522,893	SH		SOLE		1,522,893	0	0
SAGIMET BIOSCIENCES INC	COM SER A	786700104	4,177,037	770,671	SH		SOLE		770,671	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	42,411,096	327,600	SH		SOLE		327,600	0	0
SHOCKWAVE MED INC	COM	82489T104	43,960,050	135,000	SH		SOLE		135,000	0	0
SPRUCE BIOSCIENCES INC	COM	85209E109	2,050,511	2,609,125	SH		SOLE		2,609,125	0	0
STRUCTURE THERAPEUTICS INC	SPONSORED ADS	86366E106	17,686,136	412,649	SH		SOLE		412,649	0	0
SURGERY PARTNERS INC	COM	86881A100	29,382,550	985,000	SH		SOLE		985,000	0	0
TALPHERA INC	COM NEW	00444T209	325,954	316,460	SH		SOLE		316,460	0	0
TRAVERE THERAPEUTICS INC	COM	89422G107	26,405,347	3,424,818	SH		SOLE		3,424,818	0	0
TRAVERE THERAPEUTICS INC	NOTE 2.500% 9/1	761299AB2	2,841,576	3,250,000	PRN		SOLE		3,250,000	0	0
ULTRAGENYX PHARMACEUTICAL IN	COM	90400D108	82,871,855	1,774,938	SH		SOLE		1,774,938	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	113,781,000	230,000	SH		SOLE		230,000	0	0
VERA THERAPEUTICS INC	CL A	92337R101	14,711,164	341,168	SH		SOLE		341,168	0	0
VIGIL NEUROSCIENCE INC	COM	92673K108	1,609,377	471,958	SH		SOLE		471,958	0	0
VIKING THERAPEUTICS INC	COM	92686J106	21,402,000	261,000	SH		SOLE		261,000	0	0
VINCERX PHARMA INC	COM NEW	92731L106	4,512,098	891,719	SH		SOLE		891,719	0	0
WARBY PARKER INC	CL A COM	93403J106	28,308,800	2,080,000	SH		SOLE		2,080,000	0	0
WEST PHARMACEUTICAL SVSC INC	COM	955306105	54,311,198	137,250	SH		SOLE		137,250	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	54,052,590	1,255,577	SH		SOLE		1,255,577	0	0
XILIO THERAPEUTICS INC	COM	98422T100	1,556,020	1,440,759	SH		SOLE		1,440,759	0	0
ZAI LAB LTD	ADR	98887Q104	20,779,910	1,297,123	SH		SOLE		1,297,123	0	0

Rock Springs Capital Management 13F-HRQuarterly holdings report by institutional manager