Affimed (AFMD) SC 13GAffimed / Gilde Healthcare Holding B.V. ownership change

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934

(Amendment No. __)*

Affimed N.V.

(Name of Issuer)

Common Shares

(Title of Class of Securities)

N01045108

(CUSIP number)

April 18, 2022

(Date of Event which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

☐ Rule 13d-1(b)

☒ Rule 13d-1(c)

☐ Rule 13d-1(d)

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Affimed N.V. (the “Issuer”)

Im Neuenheimer Feld 582, 69120 Heidelberg, Germany

Cooperatieve Gilde Healthcare V U.A.

Gilde Healthcare V Management B.V.

Gilde Healthcare Holding B.V.

Manapouri B.V. (100% owned by Edwin de Graaf)

Martemanshurk B.V. (100% owned by Pieter van der Meer)

c/o Gilde Healthcare Partners B.V.

Newtonlaan 91

3584 BP Utrecht

The Netherlands

Each of the reporting persons is organized and based in the Netherlands.

This Statement refers to the Common Shares of the Issuer.

N01045108

Not applicable.

8,125,000 shares are held of record by Cooperatieve Gilde Healthcare V U.A. Gilde Healthcare V Management B.V. is the managing director of Cooperatieve Gilde Healthcare V U.A. and may be deemed to have voting, investment and dispositive power with respect to these securities. Gilde Healthcare V Management B.V. is fully owned by Gilde Healthcare Holding B.V., which is also its sole managing director. The managing directors of Gilde Healthcare Holding B.V. are Manapouri B.V. (of which Edwin de Graaf is the owner and managing director) and Martemanshurk B.V. (of which Pieter van der Meer is the owner and managing director). Gilde Healthcare V Management B.V. disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein.

Each of Messrs. de Graaf and Manapouri B.V. and van der Meer and Martemanshurk B.V. each disclaim beneficial ownership of the shares except to the extent of his or its pecuniary interest therein.

These percentages are based on 145,919,772 common shares (“Common Shares”) of Affimed N.V. (the “Issuer”) stated to be outstanding immediately after the offering as reported in the Issuer’s prospectus supplement (Registration No. 333-260946) filed with the Securities and Exchange Commission (“SEC”) pursuant to Rule 424(b)(5) on April 14, 2022.

(i) Sole power to vote or to direct the vote:

(ii) Shared power to vote or to direct the vote:

(iii) Sole power to dispose or to direct the disposition of:

(iv) Shared power to dispose or to direct the disposition of:

Not applicable.

Not applicable.

See Item 4(a) above.

Not applicable.

Not applicable.

Not applicable.

EXHIBIT INDEX

Signatures

After reasonable inquiry and to the best knowledge and belief of the undersigned, such person certifies that the information set forth in this Statement with respect to such person is true, complete and correct.