The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| ALECTOR INC | COM | 014442107 | 819,536 | 175,866 | SH | DFND | 1 | 0 | 175,866 | 0 | |
| ARM HOLDINGS PLC | SPONSORED ADS | 042068205 | 280,411,720 | 1,960,784 | SH | DFND | 2 | 0 | 1,960,784 | 0 | |
| AUTOLUS THERAPEUTICS PLC | SPON ADR | 05280R100 | 2,534,691 | 698,262 | SH | DFND | 1 | 0 | 698,262 | 0 | |
| BARINTHUS BIOTHERAPEUTICS PL | ADS | 91864C107 | 1,801,236 | 1,513,644 | SH | DFND | 1 | 0 | 1,513,644 | 0 | |
| BEAM THERAPEUTICS INC | COM | 07373V105 | 7,879,298 | 321,604 | SH | DFND | 1 | 0 | 321,604 | 0 | |
| BENSON HILL INC | COM NEW | 082490202 | 3,158,172 | 438,635 | SH | DFND | 1 | 0 | 438,635 | 0 | |
| CROWDSTRIKE HLDGS INC | CL A | 22788C105 | 120,011,711 | 427,895 | SH | DFND | 5 | 0 | 427,895 | 0 | |
| CUE HEALTH INC | COM | 229790100 | 0 | 27,000 | SH | DFND | 4 | 0 | 27,000 | 0 | |
| DESKTOP METAL INC | COM CL A | 25058X303 | 5,159,748 | 1,104,871 | SH | DFND | 1 | 0 | 1,104,871 | 0 | |
| DEXCOM INC | COM | 252131107 | 69,516,256 | 1,036,937 | SH | DFND | 4 | 0 | 1,036,937 | 0 | |
| DIANTHUS THERAPEUTICS INC | COM | 252828108 | 5,714,124 | 208,697 | SH | DFND | 1 | 0 | 208,697 | 0 | |
| EXACT SCIENCES CORP | COM | 30063P105 | 1,580,725 | 23,205 | SH | DFND | 4 | 0 | 23,205 | 0 | |
| FOGHORN THERAPEUTICS INC | COM | 344174107 | 4,663,388 | 500,901 | SH | DFND | 1 | 0 | 500,901 | 0 | |
| FRACTYL HEALTH INC | COM | 35168W103 | 1,676,338 | 662,584 | SH | DFND | 1 | 0 | 662,584 | 0 | |
| FRESHWORKS INC | CLASS A COM | 358054104 | 21,575,168 | 1,879,370 | SH | DFND | 3 | 0 | 1,879,370 | 0 | |
| FRESHWORKS INC | CLASS A COM | 358054104 | 164,477,094 | 14,327,273 | SH | DFND | 0 | 14,327,273 | 0 | ||
| FULCRUM THERAPEUTICS INC | COM | 359616109 | 50,915 | 14,262 | SH | DFND | 4 | 0 | 14,262 | 0 | |
| GENEDX HOLDINGS CORP | COM | 81663L200 | 963,855 | 22,711 | SH | DFND | 4 | 0 | 22,711 | 0 | |
| GITLAB INC | CLASS A COM | 37637K108 | 502,944,483 | 9,758,333 | SH | DFND | 1 | 0 | 9,758,333 | 0 | |
| HYPERFINE INC | COM CL A | 44916K106 | 970,618 | 898,720 | SH | DFND | 1 | 0 | 898,720 | 0 | |
| INVITAE CORP | COM | 46185L103 | 0 | 235,606 | SH | DFND | 4 | 0 | 235,606 | 0 | |
| KRONOS BIO INC | COM | 50107A104 | 1,438,232 | 1,438,232 | SH | DFND | 1 | 0 | 1,438,232 | 0 | |
| LYELL IMMUNOPHARMA INC | COM | 55083R104 | 8,093,873 | 5,865,125 | SH | DFND | 1 | 0 | 5,865,125 | 0 | |
| MONTE ROSA THERAPEUTICS INC | COM | 61225M102 | 7,759,280 | 1,464,015 | SH | DFND | 1 | 0 | 1,464,015 | 0 | |
| OSCAR HEALTH INC | CL A | 687793109 | 10,222,965 | 481,988 | SH | DFND | 1 | 0 | 481,988 | 0 | |
| PLANET LABS PBC | COM CL A | 72703X106 | 71,232,089 | 31,942,641 | SH | DFND | 2 | 0 | 31,942,641 | 0 | |
| PRIME MEDICINE INC | COM | 74168J101 | 58,291,867 | 15,062,498 | SH | DFND | 1 | 0 | 15,062,498 | 0 | |
| QUINCE THERAPEUTICS INC | COM | 22053A107 | 147,515 | 189,122 | SH | DFND | 4 | 0 | 189,122 | 0 | |
| RANI THERAPEUTICS HLDGS INC | COM CL A | 753018100 | 968,743 | 448,492 | SH | DFND | 1 | 0 | 448,492 | 0 | |
| RAPT THERAPEUTICS INC | COM | 75382E109 | 1,085,943 | 540,270 | SH | DFND | 1 | 0 | 540,270 | 0 | |
| RELAY THERAPEUTICS INC | COM | 75943R102 | 11,074,345 | 1,564,173 | SH | DFND | 1 | 0 | 1,564,173 | 0 | |
| RELAY THERAPEUTICS INC | COM | 75943R102 | 32,426 | 4,580 | SH | DFND | 4 | 0 | 4,580 | 0 | |
| REPLIGEN CORP | COM | 759916109 | 56,998 | 383 | SH | DFND | 4 | 0 | 383 | 0 | |
| REVOLUTION MEDICINES INC | COM | 76155X100 | 190,633,169 | 4,203,598 | SH | DFND | 1 | 0 | 4,203,598 | 0 | |
| REVOLUTION MEDICINES INC | COM | 76155X100 | 2,384,367 | 52,577 | SH | DFND | 4 | 0 | 52,577 | 0 | |
| SANA BIOTECHNOLOGY INC | COM | 799566104 | 11,700,000 | 2,812,500 | SH | DFND | 1 | 0 | 2,812,500 | 0 | |
| SNOWFLAKE INC | CL A | 833445109 | 13,157,672 | 114,554 | SH | DFND | 2 | 0 | 114,554 | 0 | |
| SPERO THERAPEUTICS INC | COM | 84833T103 | 1,192,572 | 889,979 | SH | DFND | 1 | 0 | 889,979 | 0 | |
| TAYSHA GENE THERAPIES INC | COM SHS | 877619106 | 1,288,173 | 640,882 | SH | DFND | 1 | 0 | 640,882 | 0 | |
| TEMPUS AI INC | CL A | 88023B103 | 87,792,373 | 1,551,102 | SH | DFND | 2 | 0 | 1,551,102 | 0 | |
| TENAYA THERAPEUTICS INC | COM | 87990A106 | 1,767,311 | 915,705 | SH | DFND | 1 | 0 | 915,705 | 0 | |
| TSCAN THERAPEUTICS INC | COM | 89854M101 | 5,363,858 | 1,077,080 | SH | DFND | 1 | 0 | 1,077,080 | 0 | |
| UIPATH INC | CL A | 90364P105 | 90,039,514 | 7,034,337 | SH | DFND | 3 | 0 | 7,034,337 | 0 | |
| VERA THERAPEUTICS INC | CL A | 92337R101 | 10,663,869 | 241,264 | SH | DFND | 1 | 0 | 241,264 | 0 | |
| VERVE THERAPEUTICS INC | COM | 92539P101 | 58,895,487 | 12,168,489 | SH | DFND | 1 | 0 | 12,168,489 | 0 | |
| VERVE THERAPEUTICS INC | COM | 92539P101 | 874,089 | 180,597 | SH | DFND | 4 | 0 | 180,597 | 0 | |
