Evelo Biosciences, Inc.
620 Memorial Drive
Cambridge, Massachusetts 02139
August 26, 2021
VIA EDGAR TRANSMISSION
Securities and Exchange Commission
Division of Corporation Finance
Mail Stop 3010
100 F Street, N.E.
Washington, D.C. 20549
| Re: | EVELO BIOSCIENCES, INC. |
| | Registration Statement on Form S-3 (Registration No. 333-259005) |
Ladies and Gentlemen:
In accordance with Rule 461 under the Securities Act of 1933, as amended, we hereby request acceleration of the effective date of the Registration Statement on Form S-3 (Registration No. 333-259005) (the “Registration Statement”) of Evelo Biosciences, Inc. (the “Company”). We respectfully request that the Registration Statement become effective as of 4:30 p.m., Eastern Time, on August 30, 2021, or at such later time as the Company or its counsel may orally request via telephone call to the staff. Once the Registration Statement has been declared effective, please orally confirm that event with our counsel, Latham & Watkins LLP, by calling Peter Handrinos at (617) 948-6060 or Wesley Holmes at (617) 948-6027.
If you have any questions regarding the foregoing, please do not hesitate to contact Peter Handrinos at (617) 948-6060 or Wesley Holmes at (617) 948-6027, of Latham & Watkins LLP. Thank you in advance for your consideration.
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Very truly yours, EVELO BIOSCIENCES, INC. |
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By: | | /s/ Dominic V. Capasso |
| | Name: Dominic V. Capasso Title: Corporate Counsel |
cc: | Peter N. Handrinos, Latham & Watkins LLP |
| Wesley C. Holmes, Latham & Watkins LLP |