Sana Biotechnology® P.O. BOX 8016, CARY, NC 27512-9903 Sana Biotechnology, Inc. Important Notice Regarding the Availability of Proxy Materials Annual Meeting of Stockholders to be held on June 6, 2024 at 9:00 AM, Pacific Time For stockholders of record as of April 8, 2024 This communication presents only an overview of the more complete proxy materials that are available to you on the Internet. This is not a ballot. You cannot use this notice to vote your shares. We encourage you to access and review all of the information contained in the proxy materials before voting. To view the proxy materials, including the Notice, Proxy Statement, and Annual Report on Form 10-K of Sana Biotechnology, Inc., and to obtain information on how to vote and how to attend and participate in the Annual Meeting, visit: www.proxydocs.com/SANA. To vote your proxy while visiting this website, you will need the 12-digit control number located in the shaded box below. Under United States Securities and Exchange Commission rules, proxy materials do not have to be delivered in paper. Proxy materials can be distributed by making them available on the Internet. For a convenient way to view proxy materials and VOTE, go to www.proxydocs.com/SANA Have the 12-digit control number located in the shaded box above available when you access the website and follow the instructions. You may request a paper copy of the proxy materials. There is no charge to you for requesting a copy. In order to receive a paper copy of the proxy materials in time for this year’s meeting, you must request a copy on or before May 27, 2024 at 2:00 PM, Pacific Time. Unless requested, you will not otherwise receive a paper or e-mail copy of the proxy materials. To order a paper copy of the proxy materials, use one of the following methods. INTERNET www.investorelections.com/SANA When requesting materials via the Internet, you will need the 12-digit control number located in the shaded box above. TELEPHONE (866) 648-8133 When requesting materials via the telephone, you will need the 12-digit control number located in the shaded box above. E-MAIL paper@investorelections.com If requesting materials by e-mail, please send a blank e-mail with the 12-digit control number located in the shaded box above in the subject line. No other requests, instructions or inquiries should be included in your e-mail. Sana Biotechnology, Inc. Meeting Type: Annual Meeting of Stockholders Date: Thursday, June 6, 2024 Time: 9:00 AM, Pacific Time Place: The Annual Meeting will be a virtual meeting conducted via live audio webcast. Please visit www.proxydocs.com/SANA for registration details. You must register at www.proxydocs.com/SANA to attend and participate in the Annual Meeting online. SEE REVERSE FOR FULL AGENDA