(1) | Consists of 39,111,390 ordinary shares held by Medine GmbH and 2,294,463 ordinary shares held by a former colleague, over which shares Prof. Ugur Sahin, M.D. retains voting power pursuant to a written arrangement. Pursuant to this arrangement, Prof. Ugur Sahin, M.D. retains voting power, but not dispositive power, over such shares, and accordingly Medine GmbH and Prof. Ugur Sahin, M.D. each may be deemed beneficially to own such shares. Since the time of the initial filing on Schedule 13G by Medine GmbH and Prof. Ugur Sahin, M.D. on February 13, 2020, 285,117 shares previously held by Medine GmbH or colleagues pursuant to this and similar arrangements with colleagues have been transferred to, or disposed of by, the respective beneficiaries, and accordingly neither Medine GmbH nor Prof. Ugur Sahin, M.D. remain a beneficial owner of such shares. Neither Medine GmbH nor Prof. Ugur Sahin, M.D. has sold any ordinary shares or ADSs since the initial filing on Schedule 13G by such persons on February 13, 2020. |