Ikarian Capital 13FHR Quarterly holdings report by institutional manager | SEC 15 May 24

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
Expires:	Oct 31, 2018
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	8,207,136	257,600	SH	Put	SOLE		257,600	0	0
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	8,207,136	257,600	SH	Call	SOLE		257,600	0	0
ABEONA THERAPEUTICS INC	COM NEW	00289Y206	6,442,299	888,593	SH		SOLE		888,593	0	0
ABEONA THERAPEUTICS INC	COM NEW	00289Y206	489,375	67,500	SH	Call	SOLE		67,500	0	0
ACELYRIN INC	COM	00445A100	10,559,295	1,564,340	SH		SOLE		1,564,340	0	0
ACHILLES THERAPEUTICS PLC	SPONSORED ADS	00449L102	1,803,976	1,443,181	SH		SOLE		1,443,181	0	0
ACUMEN PHARMACEUTICALS INC	COM	00509G209	1,079,063	266,435	SH		SOLE		266,435	0	0
AEON BIOPHARMA INC	CL A	00791X100	2,992,534	257,977	SH		SOLE		257,977	0	0
AEROVATE THERAPEUTICS INC	COM	008064107	10,880,725	367,965	SH		SOLE		367,965	0	0
ALEXANDRIA REAL ESTATE EQ IN	COM	015271109	9,449,103	73,300	SH	Put	SOLE		73,300	0	0
ALLAKOS INC	COM	01671P100	1,175,171	932,675	SH		SOLE		932,675	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	7,702,802	51,541	SH		SOLE		51,541	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	20,429,815	136,700	SH	Put	SOLE		136,700	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	18,053,560	120,800	SH	Call	SOLE		120,800	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	10,360,508	261,365	SH		SOLE		261,365	0	0
ALPINE IMMUNE SCIENCES INC	COM	02083G100	4,082,920	103,000	SH	Call	SOLE		103,000	0	0
AMGEN INC	COM	031162100	17,059,200	60,000	SH	Call	SOLE		60,000	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	941,321	331,451	SH		SOLE		331,451	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	529,376	186,400	SH	Put	SOLE		186,400	0	0
AMYLYX PHARMACEUTICALS INC	COM	03237H101	3,010,684	1,060,100	SH	Call	SOLE		1,060,100	0	0
ANEBULO PHARMACEUTICALS INC	COM	034569103	453,064	157,862	SH		SOLE		157,862	0	0
ANNEXON INC	COM	03589W102	10,073,850	1,405,000	SH		SOLE		1,405,000	0	0
ANNOVIS BIO INC	COM	03615A108	2,997,610	251,900	SH	Put	SOLE		251,900	0	0
ANNOVIS BIO INC	COM	03615A108	2,975,000	250,000	SH	Call	SOLE		250,000	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	2,062,708	35,092	SH		SOLE		35,092	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	5,878,000	100,000	SH	Put	SOLE		100,000	0	0
ARCUTIS BIOTHERAPEUTICS INC	COM	03969K108	5,843,352	589,642	SH		SOLE		589,642	0	0
ASLAN PHARMACEUTICALS LTD	SPON ADS NEW	04522R200	6,273	35,420	SH		SOLE		35,420	0	0
ASTRAZENECA PLC	SPONSORED ADR	046353108	20,948,300	309,200	SH	Call	SOLE		309,200	0	0
ASTRIA THERAPEUTICS INC	COM	04635X102	1,980,170	140,687	SH		SOLE		140,687	0	0
ASTRIA THERAPEUTICS INC	COM	04635X102	2,163,329	153,700	SH	Put	SOLE		153,700	0	0
ASTRIA THERAPEUTICS INC	COM	04635X102	5,630,000	400,000	SH	Call	SOLE		400,000	0	0
AVALO THERAPEUTICS INC	COM NEW	05338F306	43,422,439	1,996,434	SH		SOLE		1,996,434	0	0
AVROBIO INC	COM	05455M100	965,198	754,061	SH		SOLE		754,061	0	0
BIOHAVEN LTD	COM	G1110E107	12,234,153	223,700	SH	Call	SOLE		223,700	0	0
BIOMEA FUSION INC	COM	09077A106	1,539,850	103,000	SH	Put	SOLE		103,000	0	0
BIOMEA FUSION INC	COM	09077A106	16,110,120	1,077,600	SH	Call	SOLE		1,077,600	0	0
BIOMX INC	COM	09090D103	4,867,797	10,817,327	SH		SOLE		10,817,327	0	0
BRAINSTORM CELL THERAPEUTICS	COM NEW	10501E201	50,960	90,242	SH		SOLE		90,242	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	8,719,842	282,013	SH		SOLE		282,013	0	0
BRIDGEBIO PHARMA INC	COM	10806X102	12,040,248	389,400	SH	Call	SOLE		389,400	0	0
CABALETTA BIO INC	COM	12674W109	3,412,000	200,000	SH	Put	SOLE		200,000	0	0
CATALYST PHARMACEUTICALS INC	COM	14888U101	8,263,073	518,386	SH		SOLE		518,386	0	0
CERVOMED INC	COM	15713L109	5,530,138	237,345	SH		SOLE		237,345	0	0
CHEMOMAB THERAPEUTICS LTD	SPONSORED ADS	16385C104	166,232	213,392	SH		SOLE		213,392	0	0
CORBUS PHARMACEUTICALS HLDGS	COM NEW	21833P301	21,945,794	559,271	SH		SOLE		559,271	0	0
CORCEPT THERAPEUTICS INC	COM	218352102	25,051,455	994,500	SH	Put	SOLE		994,500	0	0
CORCEPT THERAPEUTICS INC	COM	218352102	7,040,605	279,500	SH	Call	SOLE		279,500	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	30,133,984	643,751	SH		SOLE		643,751	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	14,061,724	300,400	SH	Put	SOLE		300,400	0	0
CRINETICS PHARMACEUTICALS IN	COM	22663K107	407,247	8,700	SH	Call	SOLE		8,700	0	0
CYBIN INC	COM	23256X100	5,769,768	13,953,488	SH		SOLE		13,953,488	0	0
CYTOKINETICS INC	COM NEW	23282W605	10,176,256	145,147	SH		SOLE		145,147	0	0
CYTOKINETICS INC	COM NEW	23282W605	7,011,000	100,000	SH	Put	SOLE		100,000	0	0
DISC MEDICINE INC	COM	254604101	1,579,660	25,372	SH		SOLE		25,372	0	0
DISC MEDICINE INC	COM	254604101	24,692,316	396,600	SH	Put	SOLE		396,600	0	0
DISC MEDICINE INC	COM	254604101	3,088,096	49,600	SH	Call	SOLE		49,600	0	0
ELEVATION ONCOLOGY INC	COM	28623U101	759,697	148,089	SH		SOLE		148,089	0	0
EYEPOINT PHARMACEUTICALS INC	COM NEW	30233G209	21,642	1,047	SH		SOLE		1,047	0	0
EYEPOINT PHARMACEUTICALS INC	COM NEW	30233G209	13,604,994	658,200	SH	Put	SOLE		658,200	0	0
EYEPOINT PHARMACEUTICALS INC	COM NEW	30233G209	4,268,355	206,500	SH	Call	SOLE		206,500	0	0
FINCH THERAPEUTICS GROUP INC	COM NEW	31773D200	18,126	6,892	SH		SOLE		6,892	0	0
GLYCOMIMETICS INC	COM	38000Q102	518,400	172,800	SH	Put	SOLE		172,800	0	0
GLYCOMIMETICS INC	COM	38000Q102	518,400	172,800	SH	Call	SOLE		172,800	0	0
HOOKIPA PHARMA INC	COM	43906K100	377,913	530,776	SH		SOLE		530,776	0	0
IBIO INC	CON NEW	451033708	2,436,000	600,000	SH		SOLE		600,000	0	0
IMMATICS N.V	SHS	N44445109	519,351	49,415	SH		SOLE		49,415	0	0
IMMUNIC INC	COM	4525EP101	2,128,339	1,612,378	SH		SOLE		1,612,378	0	0
IMMUNOVANT INC	COM	45258J102	8,947,446	276,925	SH		SOLE		276,925	0	0
INFLARX NV	COM	N44821101	1,085,680	704,987	SH		SOLE		704,987	0	0
INSMED INC	COM PAR $.01	457669307	1,392,718	51,335	SH		SOLE		51,335	0	0
INSMED INC	COM PAR $.01	457669307	1,923,517	70,900	SH	Put	SOLE		70,900	0	0
INSMED INC	COM PAR $.01	457669307	9,419,536	347,200	SH	Call	SOLE		347,200	0	0
ITEOS THERAPEUTICS INC	COM	46565G104	1,382,073	101,325	SH		SOLE		101,325	0	0
JASPER THERAPEUTICS INC	COM NEW	471871202	3,087,939	105,175	SH		SOLE		105,175	0	0
KARYOPHARM THERAPEUTICS INC	COM	48576U106	618,126	409,355	SH		SOLE		409,355	0	0
KEZAR LIFE SCIENCES INC	COM	49372L100	783,484	868,992	SH		SOLE		868,992	0	0
KODIAK SCIENCES INC	COM	50015M109	2,506,842	476,586	SH		SOLE		476,586	0	0
KRYSTAL BIOTECH INC	COM	501147102	66,723,750	375,000	SH	Put	SOLE		375,000	0	0
KRYSTAL BIOTECH INC	COM	501147102	17,793,000	100,000	SH	Call	SOLE		100,000	0	0
LANTHEUS HLDGS INC	COM	516544103	10,580,800	170,000	SH	Call	SOLE		170,000	0	0
LARIMAR THERAPEUTICS INC	COM	517125100	3,328,427	438,528	SH		SOLE		438,528	0	0
LENZ THERAPEUTICS INC	COM	52635N103	1,898,050	85,000	SH		SOLE		85,000	0	0
LONGBOARD PHARMACEUTICALS IN	COM	54300N103	5,098	236	SH		SOLE		236	0	0
LYRA THERAPEUTICS INC	COM	55234L105	6,573,477	1,056,829	SH		SOLE		1,056,829	0	0
MACROGENICS INC	COM	556099109	4,683,418	318,167	SH		SOLE		318,167	0	0
MACROGENICS INC	COM	556099109	7,705,920	523,500	SH	Call	SOLE		523,500	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	13,725,856	51,400	SH	Put	SOLE		51,400	0	0
MARINUS PHARMACEUTICALS INC	COM NEW	56854Q200	4,862,842	537,925	SH		SOLE		537,925	0	0
MARINUS PHARMACEUTICALS INC	COM NEW	56854Q200	1,918,288	212,200	SH	Put	SOLE		212,200	0	0
MARINUS PHARMACEUTICALS INC	COM NEW	56854Q200	2,740,928	303,200	SH	Call	SOLE		303,200	0	0
MILESTONE PHARMACEUTICALS IN	COM	59935V107	834,174	466,019	SH		SOLE		466,019	0	0
MIND MEDICINE MINDMED INC	COM NEW	60255C885	2,796,321	297,481	SH		SOLE		297,481	0	0
MOONLAKE IMMUNOTHERAPEUTICS	CLASS A ORD	61559X104	7,936,340	158,000	SH	Put	SOLE		158,000	0	0
NURIX THERAPEUTICS INC	COM	67080M103	4,410,000	300,000	SH		SOLE		300,000	0	0
NUVALENT INC	COM	670703107	7,629,219	101,601	SH		SOLE		101,601	0	0
NUVATION BIO INC	COM CL A	67080N101	2,305,146	633,282	SH		SOLE		633,282	0	0
NYXOAH S A	SHS	B6S7WD106	683,929	50,699	SH		SOLE		50,699	0	0
PRAXIS PRECISION MEDICINES I	COM NEW	74006W207	10,275,036	168,388	SH		SOLE		168,388	0	0
PRAXIS PRECISION MEDICINES I	COM NEW	74006W207	1,330,236	21,800	SH	Call	SOLE		21,800	0	0
PROQR THRAPEUTICS N V	SHS EURO	N71542109	1,097,734	483,583	SH		SOLE		483,583	0	0
PROTARA THERAPEUTICS INC	COM STK	74365U107	812,830	202,701	SH		SOLE		202,701	0	0
PYXIS ONCOLOGY INC	COMMON STOCK	747324101	7,081,858	1,662,408	SH		SOLE		1,662,408	0	0
Q32 BIO INC	COM	746964105	380,588	22,335	SH		SOLE		22,335	0	0
RAPT THERAPEUTICS INC	COM	75382E109	1,388,532	154,625	SH		SOLE		154,625	0	0
RAPT THERAPEUTICS INC	COM	75382E109	2,210,876	246,200	SH	Put	SOLE		246,200	0	0
RAPT THERAPEUTICS INC	COM	75382E109	783,056	87,200	SH	Call	SOLE		87,200	0	0
RELMADA THERAPEUTICS INC	COM	75955J402	187,717	40,369	SH		SOLE		40,369	0	0
ROCKET PHARMACEUTICALS INC	COM	77313F106	8,003,767	297,096	SH		SOLE		297,096	0	0
ROIVANT SCIENCES LTD	SHS	G76279101	1,060,419	100,609	SH		SOLE		100,609	0	0
SAGIMET BIOSCIENCES INC	COM SER A	786700104	2,236,103	412,565	SH		SOLE		412,565	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	19,713,910	152,278	SH		SOLE		152,278	0	0
SAREPTA THERAPEUTICS INC	COM	803607100	15,030,306	116,100	SH	Call	SOLE		116,100	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	5,180,610	291,701	SH		SOLE		291,701	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	6,434,448	362,300	SH	Call	SOLE		362,300	0	0
SOLENO THERAPEUTICS INC	COM	834203309	24,199,591	565,411	SH		SOLE		565,411	0	0
SOLENO THERAPEUTICS INC	COM	834203309	3,471,080	81,100	SH	Call	SOLE		81,100	0	0
SPDR SER TR	S&P BIOTECH	78464A870	66,423,000	700,000	SH	Put	SOLE		700,000	0	0
STOKE THERAPEUTICS INC	COM	86150R107	92,017	6,816	SH		SOLE		6,816	0	0
STRUCTURE THERAPEUTICS INC	SPONSORED ADS	86366E106	5,160,344	120,400	SH	Put	SOLE		120,400	0	0
STRUCTURE THERAPEUTICS INC	SPONSORED ADS	86366E106	85,720	2,000	SH	Call	SOLE		2,000	0	0
SYNLOGIC INC	COM NEW	87166L209	36,602	20,448	SH		SOLE		20,448	0	0
TARSUS PHARMACEUTICALS INC	COM	87650L103	25,818,568	710,277	SH		SOLE		710,277	0	0
TARSUS PHARMACEUTICALS INC	COM	87650L103	3,635,000	100,000	SH	Call	SOLE		100,000	0	0
TEMPEST THERAPEUTICS INC	COM	87978U108	412,895	105,600	SH		SOLE		105,600	0	0
TERNS PHARMACEUTICALS INC	COM	880881107	580,540	88,497	SH		SOLE		88,497	0	0
TOURMALINE BIO INC	COM	89157D105	2,484,260	108,483	SH		SOLE		108,483	0	0
TOURMALINE BIO INC	COM	89157D105	4,103,680	179,200	SH	Call	SOLE		179,200	0	0
TYRA BIOSCIENCES INC	COM	90240B106	8,216	501	SH		SOLE		501	0	0
UNIQURE NV	SHS	N90064101	2,439,492	469,133	SH		SOLE		469,133	0	0
VENTYX BIOSCIENCES INC	COM	92332V107	2,792,059	507,647	SH		SOLE		507,647	0	0
VERONA PHARMA PLC	SPONSORED ADS	925050106	6,038,738	375,310	SH		SOLE		375,310	0	0
VERU INC	COM	92536C103	662,563	946,382	SH		SOLE		946,382	0	0
VIKING THERAPEUTICS INC	COM	92686J106	16,400,000	200,000	SH	Put	SOLE		200,000	0	0
VIRIDIAN THERAPEUTICS INC	COM	92790C104	3,132,539	178,900	SH	Put	SOLE		178,900	0	0
VOYAGER THERAPEUTICS INC	COM	92915B106	1,683,779	180,857	SH		SOLE		180,857	0	0
WAVE LIFE SCIENCES LTD	SHS	Y95308105	3,640,843	590,088	SH		SOLE		590,088	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	4,614,400	107,187	SH		SOLE		107,187	0	0

Ikarian Capital 13F-HRQuarterly holdings report by institutional manager