Polar Capital 13FHR Quarterly holdings report by institutional manager | SEC 14 Nov 24

The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

OMB APPROVAL

OMB Number:		3235-0006
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COLUMN 1	COLUMN 2	COLUMN 3	COLUMN 4	COLUMN 5			COLUMN 6	COLUMN 7	COLUMN 8
			VALUE	SHRS OR	SH/	PUT/	INVESTMENT	OTHER	VOTING AUTHORITY
NAME OF ISSUER	TITLE OF CLASS	CUSIP	(x$1000)	PRN AMT	PRN	CALL	DISCRETION	MANAGER	SOLE	SHARED	NONE
4D MOLECULAR THERAPEUTICS IN	COM	35104E100	9,064,099	838,492	SH		DFND	1	838,492	0	0
ABBVIE INC	COM	00287Y109	45,710,893	231,471	SH		DFND	1	231,471	0	0
ACADIA HEALTHCARE COMPANY IN	COM	00404A109	24,386,154	384,579	SH		DFND	1	384,579	0	0
ADDUS HOMECARE CORP	COM	006739106	3,879,687	29,164	SH		DFND	1	29,164	0	0
ADVANCED MICRO DEVICES INC	COM	007903107	433,225,182	2,640,329	SH		DFND	1	2,640,329	0	0
AFFILIATED MANAGERS GROUP IN	COM	008252108	15,740,990	88,532	SH		DFND	1	88,532	0	0
AFLAC INC	COM	001055102	51,428,000	460,000	SH		DFND	1	460,000	0	0
AGIOS PHARMACEUTICALS INC	COM	00847X104	44,520,459	1,002,036	SH		DFND	1	1,002,036	0	0
AIR PRODS & CHEMS INC	COM	009158106	2,441,468	8,200	SH		DFND	1,2	8,200	0	0
AIR TRANS SVCS GROUP INC	NOTE 3.875% 8/1	00922RAD7	13,325,507	14,240,000	PRN		DFND	1	14,240,000	0	0
AKAMAI TECHNOLOGIES INC	NOTE 0.125% 5/0	00971TAJ0	8,362,050	7,500,000	PRN		DFND	1	7,500,000	0	0
ALCON AG	ORD SHS	H01301128	19,046,659	215,663	SH		DFND	1	215,663	0	0
ALIBABA GROUP HLDG LTD	SPONSORED ADS	01609W102	204,599	1,928	SH		DFND	1	1,928	0	0
ALLSTATE CORP	COM	020002101	12,145,186	64,040	SH		DFND	1	64,040	0	0
ALNYLAM PHARMACEUTICALS INC	COM	02043Q107	85,259,300	310,000	SH		DFND	1	310,000	0	0
ALPHABET INC	CAP STK CL A	02079K305	251,919,682	1,518,961	SH		DFND	1,2	1,518,961	0	0
ALPHABET INC	CAP STK CL C	02079K107	255,829,624	1,530,173	SH		DFND	1	1,530,173	0	0
AMAZON COM INC	COM	023135106	231,705,827	1,243,524	SH		DFND	1,2	1,243,524	0	0
AMDOCS LTD	SHS	G02602103	19,499,292	222,900	SH		DFND	1	222,900	0	0
AMERICAN EXPRESS CO	COM	025816109	8,364,622	30,843	SH		DFND	1	30,843	0	0
AMGEN INC	COM	031162100	123,064,243	381,938	SH		DFND	1	381,938	0	0
AMPHENOL CORP NEW	CL A	032095101	157,899,296	2,423,255	SH		DFND	1	2,423,255	0	0
ANALOG DEVICES INC	COM	032654105	20,523,568	89,167	SH		DFND	1,2	89,167	0	0
ANSYS INC	COM	03662Q105	446,082	1,400	SH		DFND	1,2	1,400	0	0
APELLIS PHARMACEUTICALS INC	COM	03753U106	31,204,880	1,082,000	SH		DFND	1	1,082,000	0	0
APPLE INC	COM	037833100	10,963,116	47,052	SH	Call	DFND	1	47,052	0	0
APPLE INC	COM	037833100	304,473,915	1,306,755	SH		DFND	1	1,306,755	0	0
APPLOVIN CORP	COM CL A	03831W108	55,399,284	424,353	SH		DFND	1	424,353	0	0
APTARGROUP INC	COM	038336103	21,979,189	137,207	SH		DFND	1	137,207	0	0
APTIV PLC	SHS	G6095L109	288,040	4,000	SH		DFND	2	4,000	0	0
ARCH CAP GROUP LTD	ORD	G0450A105	333,161,410	2,977,846	SH		DFND	1	2,977,846	0	0
ARCUTIS BIOTHERAPEUTICS INC	COM	03969K108	64,024,660	6,884,372	SH		DFND	1	6,884,372	0	0
ARES MANAGEMENT CORPORATION	CL A COM STK	03990B101	12,309,178	78,986	SH		DFND	1	78,986	0	0
ARISTA NETWORKS INC	COM	040413106	328,756,799	856,539	SH		DFND	1	856,539	0	0
ARM HOLDINGS PLC	SPONSORED ADS	042068205	98,179,082	686,519	SH		DFND	1	686,519	0	0
ASCENDIS PHARMA A/S	NOTE 2.250% 4/0	04351PAD3	14,678,820	12,750,000	PRN		DFND	1	12,750,000	0	0
ASCENDIS PHARMA A/S	SPONSORED ADR	04351P101	33,594,750	225,000	SH		DFND	1	225,000	0	0
AUTODESK INC	COM	052769106	3,622,562	13,150	SH		DFND	1,2	13,150	0	0
AVADEL PHARMACEUTICALS PLC	COM SHS	G29687103	63,398,277	4,834,028	SH		DFND	1	4,834,028	0	0
AVANTOR INC	COM	05352A100	17,557,012	678,663	SH		DFND	1	678,663	0	0
AVIDITY BIOSCIENCES INC	COM	05370A108	70,829,847	1,542,126	SH		DFND	1	1,542,126	0	0
AXIS CAP HLDGS LTD	SHS	G0692U109	14,562,818	182,927	SH		DFND	1	182,927	0	0
AXON ENTERPRISE INC	COM	05464C101	141,069,989	353,028	SH		DFND	1	353,028	0	0
BBB FOODS INC	CL A COM	G0896C103	41,765,730	1,392,191	SH		DFND	1	1,392,191	0	0
BERKLEY W R CORP	COM	084423102	165,935,250	2,925,000	SH		DFND	1	2,925,000	0	0
BERKSHIRE HATHAWAY INC DEL	CL B NEW	084670702	50,530,104	109,786	SH		DFND	1	109,786	0	0
BICYCLE THERAPEUTICS PLC	SPONSORED ADS	088786108	22,692,911	1,002,780	SH		DFND	1	1,002,780	0	0
BIOCERES CROP SOLUTIONS CORP	SHS	G1117K114	12,976,465	1,648,852	SH		DFND	1	1,648,852	0	0
BLACKSTONE INC	COM	09260D107	8,645,720	56,460	SH		DFND	1	56,460	0	0
BLOCK INC	CL A	852234103	10,400,048	154,924	SH		DFND	1	154,924	0	0
BLOOM ENERGY CORP	NOTE 3.000% 6/0	093712AK3	8,696,775	9,500,000	PRN		DFND	1	9,500,000	0	0
BLUEPRINT MEDICINES CORP	COM	09627Y109	81,122,963	877,005	SH		DFND	1	877,005	0	0
BOOKING HOLDINGS INC	COM	09857L108	18,811,328	4,466	SH		DFND	1	4,466	0	0
BOSTON SCIENTIFIC CORP	COM	101137107	45,786,309	546,376	SH		DFND	1	546,376	0	0
BOWHEAD SPECIALTY HLDGS INC	COM SHS	10240L102	5,917,449	211,262	SH		DFND	1	211,262	0	0
BRAZE INC	COM CL A	10576N102	5,586,994	172,758	SH		DFND	1	172,758	0	0
BRIDGEBIO PHARMA INC	NOTE 2.500% 3/1	10806XAB8	12,892,375	12,500,000	PRN		DFND	1	12,500,000	0	0
BROADCOM INC	COM	11135F101	516,558,495	2,994,542	SH		DFND	1,2	2,994,542	0	0
BROWN & BROWN INC	COM	115236101	42,735,000	412,500	SH		DFND	1	412,500	0	0
BRUKER CORP	COM	116794108	21,926,619	317,501	SH		DFND	1	317,501	0	0
CADENCE DESIGN SYSTEM INC	COM	127387108	37,911,405	139,879	SH		DFND	1	139,879	0	0
CAMTEK LTD	ORD	M20791105	3,046,757	38,156	SH		DFND	1	38,156	0	0
CANADIAN NAT RES LTD	COM	136385101	14,434,013	360,272	SH		DFND	1	360,272	0	0
CANNAE HLDGS INC	COM	13765N107	8,318,127	436,418	SH		DFND	1	436,418	0	0
CARRIER GLOBAL CORPORATION	COM	14448C104	5,779,182	71,800	SH		DFND	1,2	71,800	0	0
CELESTICA INC	COM	15101Q207	8,909,603	174,288	SH		DFND	1	174,288	0	0
CELLDEX THERAPEUTICS INC NEW	COM NEW	15117B202	92,482,609	2,720,877	SH		DFND	1	2,720,877	0	0
CELLEBRITE DI LTD	ORDINARY SHARES	M2197Q107	4,671,365	277,397	SH		DFND	1	277,397	0	0
CENOVUS ENERGY INC	COM	15135U109	20,534,801	1,017,617	SH		DFND	1	1,017,617	0	0
CENTENE CORP DEL	COM	15135B101	19,686,021	261,504	SH		DFND	1	261,504	0	0
CENTESSA PHARMACEUTICALS PLC	SPONSORED ADS	152309100	10,233,600	640,000	SH		DFND	1	640,000	0	0
CERUS CORP	COM	157085101	23,560	13,540	SH		DFND	1	13,540	0	0
CG ONCOLOGY INC	COM	156944100	36,486,985	967,055	SH		DFND	1	967,055	0	0
CHEFS WHSE INC	NOTE 2.375%12/1	163086AE1	3,524,854	3,000,000	PRN		DFND	1	3,000,000	0	0
CHEMED CORP NEW	COM	16359R103	5,203,198	8,658	SH		DFND	1	8,658	0	0
CHUBB LIMITED	COM	H1467J104	237,973,083	825,178	SH		DFND	1	825,178	0	0
CIENA CORP	COM NEW	171779309	62,522,842	1,015,146	SH		DFND	1	1,015,146	0	0
CITIGROUP INC	COM NEW	172967424	8,412,438	134,384	SH		DFND	1	134,384	0	0
CLOUDFLARE INC	CL A COM	18915M107	290,840,399	3,595,505	SH		DFND	1	3,595,505	0	0
COCA-COLA EUROPACIFIC PARTNE	SHS	G25839104	8,587,766	109,051	SH		DFND	1	109,051	0	0
COGNEX CORP	COM	192422103	3,584,250	88,500	SH		DFND	1,2	88,500	0	0
COHERENT CORP	COM	19247G107	64,303,091	723,238	SH		DFND	1	723,238	0	0
COMMVAULT SYS INC	COM	204166102	19,766,802	128,481	SH		DFND	1	128,481	0	0
CONTINEUM THERAPEUTICS INC	CL A	21217B100	4,145,743	216,601	SH		DFND	1	216,601	0	0
CORE & MAIN INC	CL A	21874C102	8,178,302	184,196	SH		DFND	1	184,196	0	0
CREDO TECHNOLOGY GROUP HOLDI	ORDINARY SHARES	G25457105	9,270,800	301,000	SH		DFND	1,2	301,000	0	0
CRH PLC	ORD	G25508105	30,067,699	324,215	SH		DFND	1	324,215	0	0
CRITEO S A	SPONS ADS	226718104	20,783,759	516,495	SH		DFND	1	516,495	0	0
CROWDSTRIKE HLDGS INC	CL A	22788C105	5,602,388	19,975	SH		DFND	1	19,975	0	0
CYBERARK SOFTWARE LTD	SHS	M2682V108	253,156,847	868,135	SH		DFND	1	868,135	0	0
CYTOKINETICS INC	NOTE 3.500% 7/0	23282WAC4	2,593,200	2,000,000	PRN		DFND	1	2,000,000	0	0
CYTOKINETICS INC	COM NEW	23282W605	123,438,322	2,337,847	SH		DFND	1	2,337,847	0	0
DATADOG INC	CL A COM	23804L103	23,802,462	206,870	SH		DFND	1	206,870	0	0
DAY ONE BIOPHARMACEUTICALS I	COM	23954D109	2,577,050	185,000	SH		DFND	1	185,000	0	0
DEERE & CO	COM	244199105	6,408,102	15,355	SH		DFND	1	15,355	0	0
DEXCOM INC	COM	252131107	11,229,200	167,500	SH		DFND	1	167,500	0	0
DOORDASH INC	CL A	25809K105	86,397,038	605,318	SH		DFND	1	605,318	0	0
DOXIMITY INC	CL A	26622P107	5,228,400	120,000	SH		DFND	1	120,000	0	0
DUPONT DE NEMOURS INC	COM	26614N102	10,867,143	121,952	SH		DFND	1	121,952	0	0
EATON CORP PLC	SHS	G29183103	47,611,687	143,651	SH		DFND	1	143,651	0	0
ECOLAB INC	COM	278865100	12,331,928	48,298	SH		DFND	1	48,298	0	0
ELASTIC N V	ORD SHS	N14506104	53,127,131	692,120	SH		DFND	1	692,120	0	0
ELEVANCE HEALTH INC	COM	036752103	22,886,240	44,012	SH		DFND	1	44,012	0	0
ELI LILLY & CO	COM	532457108	86,764,534	97,935	SH		DFND	1	97,935	0	0
ENCOMPASS HEALTH CORP	COM	29261A100	347,904	3,600	SH		DFND	1	3,600	0	0
ENERSYS	COM	29275Y102	3,592,160	35,200	SH		DFND	1,2	35,200	0	0
ENLIVEN THERAPEUTICS INC	COM	29337E102	16,601,000	650,000	SH		DFND	1	650,000	0	0
ENVISTA HOLDINGS CORPORATION	COM	29415F104	2,032,296	102,849	SH		DFND	1	102,849	0	0
ESSENT GROUP LTD	COM	G3198U102	151,081,500	2,350,000	SH		DFND	1	2,350,000	0	0
ESTABLISHMENT LABS HLDGS INC	COM	G31249108	23,647,877	546,519	SH		DFND	1	546,519	0	0
EVEREST GROUP LTD	COM	G3223R108	141,058,800	360,000	SH		DFND	1	360,000	0	0
EXELIXIS INC	COM	30161Q104	5,190,000	200,000	SH		DFND	1	200,000	0	0
FABRINET	SHS	G3323L100	82,428,895	348,625	SH		DFND	1	348,625	0	0
FERGUSON ENTERPRISES INC	COMMON STOCK NEW	31488V107	725,264,659	76,703	SH		DFND	1	76,703	0	0
FIDELITY NATL INFORMATION SV	COM	31620M106	38,075,346	454,631	SH		DFND	1	454,631	0	0
FIRST AMERN FINL CORP	COM	31847R102	44,556,750	675,000	SH		DFND	1	675,000	0	0
FIRST SOLAR INC	COM	336433107	168,065,189	673,770	SH		DFND	1,2	673,770	0	0
FISERV INC	COM	337738108	21,491,889	119,632	SH		DFND	1	119,632	0	0
FLUENCE ENERGY INC	COM CL A	34379V103	5,325,495	234,500	SH		DFND	1,2	234,500	0	0
FLUOR CORP	NOTE 1.125% 8/1	343412AJ1	1,217,630	1,000,000	PRN		DFND	1	1,000,000	0	0
GE HEALTHCARE TECHNOLOGIES I	COMMON STOCK	36266G107	10,802,323	115,102	SH		DFND	1	115,102	0	0
GE VERNOVA INC	COM	36828A101	11,729,080	46,000	SH		DFND	1,2	46,000	0	0
GLOBAL E ONLINE LTD	SHS	M5216V106	8,218,203	213,793	SH		DFND	1	213,793	0	0
GLOBANT S A	COM	L44385109	62,645,329	316,167	SH		DFND	1	316,167	0	0
GLOBE LIFE INC	COM	37959E102	12,026,716	113,556	SH		DFND	1	113,556	0	0
GOLDMAN SACHS GROUP INC	COM	38141G104	10,429,987	21,066	SH		DFND	1	21,066	0	0
GOODRX HLDGS INC	COM CL A	38246G108	85,778	12,360	SH		DFND	1	12,360	0	0
H WORLD GROUP LTD	SPONSORED ADS	44332N106	6,415,363	172,456	SH		DFND	1	172,456	0	0
HAGERTY INC	CL A COM	405166109	50,850,000	5,000,000	SH		DFND	1	5,000,000	0	0
HCA HEALTHCARE INC	COM	40412C101	67,174,344	165,279	SH		DFND	1	165,279	0	0
HEALTHEQUITY INC	COM	42226A107	258,646	3,160	SH		DFND	1	3,160	0	0
HOLOGIC INC	COM	436440101	2,109,244	25,893	SH		DFND	1	25,893	0	0
HUBSPOT INC	COM	443573100	57,588,760	108,331	SH		DFND	1	108,331	0	0
HYATT HOTELS CORP	COM CL A	448579102	16,704,102	109,751	SH		DFND	1	109,751	0	0
ICON PLC	SHS	G4705A100	24,408,996	84,957	SH		DFND	1	84,957	0	0
IDEAYA BIOSCIENCES INC	COM	45166A102	20,750,400	655,000	SH		DFND	1	655,000	0	0
IMMUNOCORE HLDGS PLC	ADS	45258D105	15,619,633	501,755	SH		DFND	1	501,755	0	0
IMPINJ INC	NOTE 1.125% 5/1	453204AD1	8,616,770	4,300,000	PRN		DFND	1	4,300,000	0	0
IMPINJ INC	COM	453204109	61,965,642	286,189	SH		DFND	1	286,189	0	0
INSMED INC	COM PAR $.01	457669307	49,640,000	680,000	SH		DFND	1	680,000	0	0
INSULET CORP	NOTE 0.375% 9/0	45784PAK7	3,587,640	3,000,000	PRN		DFND	1	3,000,000	0	0
INSULET CORP	COM	45784P101	29,606,731	127,204	SH		DFND	1	127,204	0	0
INTEGER HLDGS CORP	COM	45826H109	44,427,110	341,747	SH		DFND	1	341,747	0	0
INTERACTIVE BROKERS GROUP IN	COM CL A	45841N107	32,420,432	232,638	SH		DFND	1	232,638	0	0
INTERCONTINENTAL EXCHANGE IN	COM	45866F104	44,735,188	278,481	SH		DFND	1	278,481	0	0
INTUITIVE SURGICAL INC	COM NEW	46120E602	140,706,115	286,413	SH		DFND	1	286,413	0	0
IRHYTHM TECHNOLOGIES INC	COM	450056106	4,243,930	57,165	SH		DFND	1	57,165	0	0
JASPER THERAPEUTICS INC	COM NEW	471871202	10,938,730	581,538	SH		DFND	1	581,538	0	0
JPMORGAN CHASE & CO.	COM	46625H100	52,702,981	249,943	SH		DFND	1	249,943	0	0
KE HLDGS INC	SPONSORED ADS	482497104	34,757,385	1,745,725	SH		DFND	1	1,745,725	0	0
KKR & CO INC	COM	48251W104	10,757,180	82,380	SH		DFND	1	82,380	0	0
KLA CORP	COM NEW	482480100	262,784,417	339,335	SH		DFND	1	339,335	0	0
KLAVIYO INC	COM SER A	49845K101	11,206,438	316,745	SH		DFND	1	316,745	0	0
LATTICE SEMICONDUCTOR CORP	COM	518415104	3,104,595	58,500	SH		DFND	1,2	58,500	0	0
LEGEND BIOTECH CORP	SPONSORED ADS	52490G102	24,181,678	496,238	SH		DFND	1	496,238	0	0
LENNOX INTL INC	COM	526107107	7,342,124	12,150	SH		DFND	1,2	12,150	0	0
LI AUTO INC	NOTE 0.250% 5/0	50202MAB8	7,149,300	6,000,000	PRN		DFND	1	6,000,000	0	0
LIBERTY MEDIA CORP DEL	NOTE 2.250% 8/1	531229AQ5	1,098,420	1,000,000	PRN		DFND	1	1,000,000	0	0
LIBERTY MEDIA CORP DEL	COM LBTY ONE S C	531229755	13,975,728	180,495	SH		DFND	1	180,495	0	0
LIFESTANCE HEALTH GROUP INC	COM	53228F101	80,500	11,500	SH		DFND	1	11,500	0	0
LINDE PLC	SHS	G54950103	24,346,087	51,055	SH		DFND	1,2	51,055	0	0
LITTELFUSE INC	COM	537008104	14,733,311	55,545	SH		DFND	1	55,545	0	0
LIVANOVA PLC	SHS	G5509L101	6,607,641	125,764	SH		DFND	1	125,764	0	0
LIVE NATION ENTERTAINMENT IN	NOTE 2.000% 2/1	538034AU3	10,342,935	9,500,000	PRN		DFND	1	9,500,000	0	0
LONGBOARD PHARMACEUTICALS IN	COM	54300N103	36,754,324	1,102,740	SH		DFND	1	1,102,740	0	0
LOWES COS INC	COM	548661107	15,938,168	58,845	SH		DFND	1	58,845	0	0
LUMENTUM HLDGS INC	COM	55024U109	11,852,060	187,000	SH		DFND	1,2	187,000	0	0
MACOM TECH SOLUTIONS HLDGS I	COM	55405Y100	122,051,330	1,096,992	SH		DFND	1	1,096,992	0	0
MADRIGAL PHARMACEUTICALS INC	COM	558868105	21,322,805	100,475	SH		DFND	1	100,475	0	0
MAKEMYTRIP LIMITED MAURITIUS	SHS	V5633W109	91,838,318	988,040	SH		DFND	1	988,040	0	0
MARKEL GROUP INC	COM	570535104	130,192,140	83,000	SH		DFND	1	83,000	0	0
MARRIOTT INTL INC NEW	CL A	571903202	8,297,025	33,375	SH		DFND	1	33,375	0	0
MARSH & MCLENNAN COS INC	COM	571748102	222,281,299	996,375	SH		DFND	1	996,375	0	0
MARVELL TECHNOLOGY INC	COM	573874104	18,102,120	251,000	SH		DFND	1,2	251,000	0	0
MASTERCARD INCORPORATED	CL A	57636Q104	43,765,988	88,631	SH		DFND	1	88,631	0	0
MCKESSON CORP	COM	58155Q103	25,835,423	52,254	SH		DFND	1	52,254	0	0
MERCADOLIBRE INC	COM	58733R102	228,106,133	111,165	SH		DFND	1	111,165	0	0
MERIT MED SYS INC	COM	589889104	40,793,565	412,765	SH		DFND	1	412,765	0	0
MERUS N V	COM	N5749R100	63,301,918	1,267,052	SH		DFND	1	1,267,052	0	0
META PLATFORMS INC	CL A	30303M102	827,100,238	1,444,868	SH		DFND	1	1,444,868	0	0
MICRON TECHNOLOGY INC	COM	595112103	199,732,289	1,925,873	SH		DFND	1	1,925,873	0	0
MICROSOFT CORP	COM	594918104	8,476,910	19,700	SH	Call	DFND	1	19,700	0	0
MICROSOFT CORP	COM	594918104	690,693,033	1,605,143	SH		DFND	1	1,605,143	0	0
MIRUM PHARMACEUTICALS INC	COM	604749101	26,325,000	675,000	SH		DFND	1	675,000	0	0
MKS INSTRS INC	COM	55306N104	17,010,615	156,477	SH		DFND	1	156,477	0	0
MONDAY COM LTD	SHS	M7S64H106	66,677,300	240,045	SH		DFND	1	240,045	0	0
MONGODB INC	CL A	60937P106	57,888,694	214,125	SH		DFND	1	214,125	0	0
MONOLITHIC PWR SYS INC	COM	609839105	190,288,911	205,829	SH		DFND	1,2	205,829	0	0
MOONLAKE IMMUNOTHERAPEUTICS	CLASS A ORD	61559X104	25,210,000	500,000	SH		DFND	1	500,000	0	0
MP MATERIALS CORP	COM CL A	553368101	5,842,150	331,000	SH		DFND	1,2	331,000	0	0
NASDAQ INC	COM	631103108	14,711,661	201,502	SH		DFND	1	201,502	0	0
NATERA INC	COM	632307104	222,797	1,755	SH		DFND	1	1,755	0	0
NETEASE INC	SPONSORED ADS	64110W102	201,701	2,157	SH		DFND	1	2,157	0	0
NETFLIX INC	COM	64110L106	137,862,938	194,373	SH		DFND	1	194,373	0	0
NEUROCRINE BIOSCIENCES INC	COM	64125C109	2,304,400	20,000	SH		DFND	1	20,000	0	0
NEWAMSTERDAM PHARMA COMPANY	ORDINARY SHARES	N62509109	24,983,000	1,505,000	SH		DFND	1	1,505,000	0	0
NOVA LTD	COM	M7516K103	12,211,016	58,611	SH		DFND	1	58,611	0	0
NU HLDGS LTD	ORD SHS CL A	G6683N103	52,047,559	3,813,008	SH		DFND	1	3,813,008	0	0
NUTANIX INC	NOTE 0.250%10/0	67059NAH1	17,150,292	14,360,000	PRN		DFND	1	14,360,000	0	0
NUTANIX INC	CL A	67059N108	51,284,726	865,565	SH		DFND	1	865,565	0	0
NUVALENT INC	COM	670703107	37,083,750	362,500	SH		DFND	1	362,500	0	0
NVENT ELECTRIC PLC	SHS	G6700G107	22,337,340	317,924	SH		DFND	1,2	317,924	0	0
NVIDIA CORPORATION	COM	67066G104	1,306,096,429	10,755,076	SH		DFND	1	10,755,076	0	0
NXP SEMICONDUCTORS N V	COM	N6596X109	6,468,270	26,950	SH		DFND	1,2	26,950	0	0
ON SEMICONDUCTOR CORP	NOTE 0.500% 3/0	682189AU9	3,540,705	3,500,000	PRN		DFND	1	3,500,000	0	0
ON SEMICONDUCTOR CORP	COM	682189105	9,882,221	136,100	SH		DFND	1,2	136,100	0	0
OPEN TEXT CORP	COM	683715106	15,157,469	377,405	SH		DFND	1	377,405	0	0
ORACLE CORP	COM	68389X105	82,344,948	483,245	SH		DFND	1	483,245	0	0
PALANTIR TECHNOLOGIES INC	CL A	69608A108	13,259,308	356,433	SH		DFND	1	356,433	0	0
PALO ALTO NETWORKS INC	COM	697435105	102,557,774	300,052	SH		DFND	1	300,052	0	0
PDD HOLDINGS INC	SPONSORED ADS	722304102	71,435,145	529,895	SH		DFND	1	529,895	0	0
PENUMBRA INC	COM	70975L107	17,650,343	90,836	SH		DFND	1	90,836	0	0
PLIANT THERAPEUTICS INC	COM	729139105	22,588,150	2,015,000	SH		DFND	1	2,015,000	0	0
PRIVIA HEALTH GROUP INC	COM	74276R102	191,933	10,540	SH		DFND	1	10,540	0	0
PROGRESSIVE CORP	COM	743315103	158,811,382	625,833	SH		DFND	1	625,833	0	0
PROTAGONIST THERAPEUTICS INC	COM	74366E102	15,750,000	350,000	SH		DFND	1	350,000	0	0
PURE STORAGE INC	CL A	74624M102	117,924,785	2,347,229	SH		DFND	1	2,347,229	0	0
QIAGEN NV	SHS NEW	N72482149	12,376,070	240,484	SH		DFND	1	240,484	0	0
QORVO INC	COM	74736K101	1,270,590	12,300	SH		DFND	1,2	12,300	0	0
QUALCOMM INC	COM	747525103	98,144,187	577,149	SH		DFND	1	577,149	0	0
REGENERON PHARMACEUTICALS	COM	75886F107	75,473,776	71,795	SH		DFND	1	71,795	0	0
REINSURANCE GRP OF AMERICA I	COM NEW	759351604	102,616,770	471,000	SH		DFND	1	471,000	0	0
RENAISSANCERE HLDGS LTD	COM	G7496G103	334,590,554	1,228,306	SH		DFND	1	1,228,306	0	0
RHYTHM PHARMACEUTICALS INC	COM	76243J105	78,585,000	1,500,000	SH		DFND	1	1,500,000	0	0
RLI CORP	COM	749607107	40,294,800	260,000	SH		DFND	1	260,000	0	0
ROBLOX CORP	CL A	771049103	14,301,645	323,128	SH		DFND	1	323,128	0	0
ROIVANT SCIENCES LTD	SHS	G76279101	40,390,000	3,500,000	SH		DFND	1	3,500,000	0	0
RXSIGHT INC	COM	78349D107	9,139,953	184,907	SH		DFND	1	184,907	0	0
RYAN SPECIALTY HOLDINGS INC	CL A	78351F107	100,580,850	1,515,000	SH		DFND	1	1,515,000	0	0
S&P GLOBAL INC	COM	78409V104	28,652,262	55,461	SH		DFND	1	55,461	0	0
SAMSARA INC	COM CL A	79589L106	44,323,091	921,095	SH		DFND	1	921,095	0	0
SAREPTA THERAPEUTICS INC	NOTE 1.250% 9/1	803607AD2	7,509,084	6,600,000	PRN		DFND	1	6,600,000	0	0
SCHLUMBERGER LTD	COM STK	806857108	8,733,529	208,189	SH		DFND	1	208,189	0	0
SCHOLAR ROCK HLDG CORP	COM	80706P103	23,554,783	2,940,672	SH		DFND	1	2,940,672	0	0
SEA LTD	SPONSORD ADS	81141R100	58,516,956	620,672	SH		DFND	1	620,672	0	0
SEAGATE HDD CAYMAN	NOTE 3.500% 6/0	81180WBL4	2,848,980	2,000,000	PRN		DFND	1	2,000,000	0	0
SELECT SECTOR SPDR TR	FINANCIAL	81369Y605	294,580	6,500	SH	Put	DFND	1	6,500	0	0
SERVICENOW INC	COM	81762P102	182,679,157	204,250	SH		DFND	1	204,250	0	0
SHARKNINJA INC	COM SHS	G8068L108	4,702,360	43,256	SH		DFND	1	43,256	0	0
SHOPIFY INC	CL A	82509L107	150,013,024	1,871,887	SH		DFND	1	1,871,887	0	0
SILENCE THERAPEUTICS PLC	ADS	82686Q101	18,180,000	1,000,000	SH		DFND	1	1,000,000	0	0
SITIME CORP	COM	82982T106	10,662,948	62,171	SH		DFND	1	62,171	0	0
SMURFIT WESTROCK PLC	SHS	G8267P108	3,199,691,229	527,770	SH		DFND	1	527,770	0	0
SPOTIFY TECHNOLOGY S A	SHS	L8681T102	223,174,766	605,581	SH		DFND	1	605,581	0	0
SPRINGWORKS THERAPEUTICS INC	COM	85205L107	48,060,000	1,500,000	SH		DFND	1	1,500,000	0	0
SPYRE THERAPEUTICS INC	COM NEW	00773J202	14,705,000	500,000	SH		DFND	1	500,000	0	0
SS&C TECHNOLOGIES HLDGS INC	COM	78467J100	18,420,926	248,227	SH		DFND	1	248,227	0	0
STANDARD BIOTOOLS INC	COM	34385P108	68,679	35,585	SH		DFND	1	35,585	0	0
STEREOTAXIS INC	COM NEW	85916J409	73,032	35,800	SH		DFND	1	35,800	0	0
STEVANATO GROUP S P A	ORD SHS	T9224W109	13,143,800	657,190	SH		DFND	1	657,190	0	0
STRYKER CORPORATION	COM	863667101	3,200,041	8,858	SH		DFND	1	8,858	0	0
SUPERNUS PHARMACEUTICALS INC	COM	868459108	60,424,657	1,937,930	SH		DFND	1	1,937,930	0	0
SYNDAX PHARMACEUTICALS INC	COM	87164F105	9,625,000	500,000	SH		DFND	1	500,000	0	0
SYNOPSYS INC	COM	871607107	7,910,825	15,622	SH		DFND	1	15,622	0	0
TANDEM DIABETES CARE INC	COM NEW	875372203	6,529,104	153,952	SH		DFND	1	153,952	0	0
TAYSHA GENE THERAPIES INC	COM SHS	877619106	6,080,250	3,025,000	SH		DFND	1	3,025,000	0	0
TE CONNECTIVITY PLC	ORD SHS	G87052109	226,485	1,500	SH		DFND	2	1,500	0	0
TECK RESOURCES LTD	CL B	878742204	9,671,191	185,130	SH		DFND	1	185,130	0	0
TENET HEALTHCARE CORP	COM NEW	88033G407	2,244,199	13,503	SH		DFND	1	13,503	0	0
TERADYNE INC	COM	880770102	129,562,944	967,393	SH		DFND	1	967,393	0	0
TESLA INC	COM	88160R101	127,095,668	485,784	SH		DFND	1	485,784	0	0
THE TRADE DESK INC	COM CL A	88339J105	119,476,285	1,089,615	SH		DFND	1	1,089,615	0	0
T-MOBILE US INC	COM	872590104	16,130,748	78,168	SH		DFND	1	78,168	0	0
TRANSMEDICS GROUP INC	NOTE 1.500% 6/0	89377MAB5	3,692,200	2,000,000	PRN		DFND	1	2,000,000	0	0
TRANSMEDICS GROUP INC	COM	89377M109	1,487,889	9,477	SH		DFND	1	9,477	0	0
TRAVELERS COMPANIES INC	COM	89417E109	121,742,400	520,000	SH		DFND	1	520,000	0	0
TRIMBLE INC	COM	896239100	248,360	4,000	SH		DFND	2	4,000	0	0
TRIP COM GROUP LTD	ADS	89677Q107	43,812,450	737,211	SH		DFND	1	737,211	0	0
TRUPANION INC	COM	898202106	54,574,000	1,300,000	SH		DFND	1	1,300,000	0	0
UBER TECHNOLOGIES INC	NOTE 12/1	90353TAJ9	22,164,200	20,000,000	PRN		DFND	1	20,000,000	0	0
UBER TECHNOLOGIES INC	COM	90353T100	13,331,129	177,370	SH		DFND	1,2	177,370	0	0
UNION PAC CORP	COM	907818108	17,872,265	72,510	SH		DFND	1	72,510	0	0
UNITED RENTALS INC	COM	911363109	12,400,205	15,314	SH		DFND	1	15,314	0	0
UNITEDHEALTH GROUP INC	COM	91324P102	71,285,940	121,923	SH		DFND	1	121,923	0	0
US FOODS HLDG CORP	COM	912008109	25,149,626	408,937	SH		DFND	1	408,937	0	0
VARONIS SYS INC	COM	922280102	76,259,632	1,349,728	SH		DFND	1	1,349,728	0	0
VAXCYTE INC	COM	92243G108	113,787,666	995,779	SH		DFND	1	995,779	0	0
VERTEX PHARMACEUTICALS INC	COM	92532F100	81,389,000	175,000	SH		DFND	1	175,000	0	0
VERTIV HOLDINGS CO	COM CL A	92537N108	14,505,642	145,800	SH		DFND	1,2	145,800	0	0
VISA INC	COM CL A	92826C839	57,828,034	210,322	SH		DFND	1	210,322	0	0
VTEX	SHS CL A	G9470A102	31,937,070	4,292,617	SH		DFND	1	4,292,617	0	0
WALMART INC	COM	931142103	26,693,528	330,570	SH		DFND	1	330,570	0	0
WAYFAIR INC	NOTE 3.500%11/1	94419LAR2	1,469,610	1,000,000	PRN		DFND	1	1,000,000	0	0
WELLS FARGO CO NEW	COM	949746101	12,559,648	222,334	SH		DFND	1	222,334	0	0
WINNEBAGO INDS INC	NOTE 1.500% 4/0	974637AB6	4,722,255	4,500,000	PRN		DFND	1	4,500,000	0	0
WORLD KINECT CORPORATION	NOTE 3.250% 7/0	98149GAB6	3,778,900	3,100,000	PRN		DFND	1	3,100,000	0	0
XENON PHARMACEUTICALS INC	COM	98420N105	96,245,674	2,444,645	SH		DFND	1	2,444,645	0	0
Y-MABS THERAPEUTICS INC	COM	984241109	24,077,650	1,831,000	SH		DFND	1	1,831,000	0	0
ZSCALER INC	NOTE 0.125% 7/0	98980GAB8	5,497,470	4,500,000	PRN		DFND	1	4,500,000	0	0

Polar Capital 13F-HRQuarterly holdings report by institutional manager