Haleon (HLN) F-4Registration of securities (foreign)

Exhibit 16.1

29 September 2022

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549-7561

Dear Sirs/Madams:

We have read Item 16.F “Change in Certifying Accountant” of Haleon plc’s Form F-4 dated 29 September 2022, and have the following comments:

Yours truly,

/s/ Deloitte LLP