Filed Pursuant to Rule 424(b)(3)
Registration No. 333-268888
PROSPECTUS
64,017,688 Ordinary Shares
167,000 Private Placement Warrants to Purchase Ordinary Shares
This prospectus relates to the issuance by us of up to 1,736,545 ordinary shares, with a nominal value of € 0.12 per share (“Ordinary Shares”) underlying options issued pursuant to our Rollover Option Plan (such options, the “Rollover Options,” and such plan, the “Rollover Plan”). The Rollover Options each have an exercise price of EUR 1.16392. This prospectus also relates to the issuance by us of up to 3,352,857 Ordinary Shares that are issuable upon the exercise of 3,352,857 Warrants (as defined below) and up to 1,886,137 Ordinary Shares issuable upon the achievement of a certain clinical development milestone (the “Earnout Shares”), each as have been previously registered on Form F-4 (File No. 333-266510).
This prospectus also relates to the offer and sale, from time to time, by the selling securityholders identified in this prospectus (each, a “Selling Securityholder” and collectively, the “Selling Securityholders”), or their permitted transferees, of up to 60,395,006 Ordinary Shares, which consists of (i) up to 22,960,001 Ordinary Shares (the “PIPE Shares”) issued on November 22, 2022 in a private placement pursuant to subscription agreements, dated July 25, 2022 (the “Subscription Agreements”) at a price per share of $10.00, (ii) up to 32,668,005 Ordinary Shares, required to be registered pursuant to the certain Investor Rights Agreement, dated November 22, 2022 (the “Investor Rights Agreement”), by and among us and certain of the Selling Securityholders (including the Ordinary Shares issued for no additional consideration paid at the time of issuance to Saga Investments Coöperatief U.A. (“Amgen”) and Mitsubishi Tanabe Pharma Corporation (“MTPC”), at an assumed value of $10.00 per share, in satisfaction of the payments owed to Amgen and MTPC under the share sale and purchase agreement with Amgen in 2020 (the “2020 SPA”) and the profit right and waiver agreement with MTPC (such rights, the “2020 Profit Rights”)) (the “IRA Shares”), (iii) up to 167,000 Ordinary Shares that are issuable upon the exercise of private placement warrants (the “Private Placement Warrants”) originally issued as part of a unit of Frazier Lifesciences Acquisition Corporation (“FLAC”) at a price of $10.00 per unit, with each unit consisting of one Class A ordinary share of FLAC and one-third of one Private Placement Warrant, in a private placement to Frazier Lifesciences Sponsor LLC (the “Sponsor”) in connection with the initial public offering of FLAC and (iv) up to 4,600,000 Ordinary Shares that are issuable upon the exercise of public warrants (the “Public Warrants,” and together with the Private Placement Warrants, the “Warrants”), originally issued as part of a unit of FLAC at a price of $10.00 per unit in FLAC’s initial public offering (the “FLAC IPO”), with each unit consisting of one Class A ordinary share of FLAC and one-third of one Public Warrant. This prospectus also relates to the offer and sale, from time to time, by the Selling Securityholders of up to 167,000 Private Placement Warrants. This prospectus also covers any additional securities that may become issuable by reason of share splits, share dividends or other similar transactions. Each Warrant entitles the holder thereof to purchase one Ordinary Share at an exercise price of $11.50 per share. The IRA Shares were all acquired at various prices prior to the closing of the Business Combination (as defined below). The IRA Shares initially consisted of (i) 5,326,818 Ordinary Shares that, prior to the Business Combination, originally consisted of 2,500,000 ordinary shares of NewAmsterdam Pharma Holding B.V. (“NewAmsterdam Pharma”) purchased for a price of EUR 1.00 per share, (ii) 22,628,329 Ordinary Shares that, prior to the Business Combination, originally consisted of 10,620,003 NewAmsterdam Pharma Series A preferred shares purchased for a price of EUR 14.00 per share, (iii) 2,367,568 Ordinary Shares that, prior to the Business Combination, originally consisted of 1,111,155 NewAmsterdam Pharma Series A preferred shares issued to certain NewAmsterdam Pharma holders in exchange for the extinguishment of a convertible loan at a price of $10.50 per share, (iv) 5,326,818 Ordinary Shares that, prior to the Business Combination, originally consisted of 2,500,000 NewAmsterdam Pharma non-voting shares issued to certain NewAmsterdam Pharma shareholders in exchange for the waiver of certain rights in connection with the 2020 SPA and for no additional consideration, (v) 608,779 Ordinary Shares that, prior to the Business Combination, originally consisted of 285,714 NewAmsterdam Pharma non-voting shares purchased for a price of EUR 2.48 per share, (vi) 501,000 Ordinary Shares that originally consisted of FLAC Class A ordinary shares purchased by the Sponsor as part of units of FLAC issued in a private placement in connection with the FLAC IPO, at a price of $10.00 per unit, (vii) 3,300,000 Ordinary Shares that originally consisted of FLAC Class B ordinary shares purchased by the Sponsor for a price per share of approximately $0.009 per share, (viii) 150,000 Ordinary Shares that originally consisted of FLAC Class B ordinary shares, held by the former directors of FLAC and acquired by each of them for no additional consideration and (ix) 4,910,000 Ordinary Shares and 3,746,330