The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||||||
| UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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| COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
| VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
| NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
| Adicet Bio, Inc. | COM | 007002108 | 524,840 | 364,472 | SH | DFND | 1 | 0 | 364,472 | 0 | |
| Arrowhead Pharmaceuticals, Inc. | COM | 04280A100 | 4,795,973 | 247,598 | SH | DFND | 1 | 0 | 247,598 | 0 | |
| BiomX Inc. | COM | 09090D103 | 196,167 | 192,321 | SH | DFND | 1 | 0 | 192,321 | 0 | |
| Clearside Biomedical, Inc. | COM | 185063104 | 104,751 | 82,481 | SH | DFND | 1 | 0 | 82,481 | 0 | |
| Contineum Therapeutics Inc. | CL A | 21217B100 | 37,881,371 | 1,979,173 | SH | DFND | 1 | 0 | 1,979,173 | 0 | |
| CVRx, Inc. | COM | 126638105 | 36,151,218 | 4,103,430 | SH | DFND | 1 | 0 | 4,103,430 | 0 | |
| Fate Therapeutics, Inc. | COM | 31189P102 | 11,826,724 | 3,379,064 | SH | DFND | 1 | 0 | 3,379,064 | 0 | |
| Legend Biotech Corporation | SPONSORED ADS | 52490G102 | 39,694,776 | 814,586 | SH | DFND | 1 | 0 | 814,586 | 0 | |
| MeiraGTx Holdings plc | COM | G59665102 | 27,693,237 | 6,641,064 | SH | DFND | 1 | 0 | 6,641,064 | 0 | |
| Nano-X Imaging Ltd. | ORD SHS | M70700105 | 965,820 | 158,852 | SH | DFND | 1 | 0 | 158,852 | 0 | |
| Nanobiotix S.A. | SPONSORED ADS | 63009J107 | 32,336,942 | 5,623,816 | SH | DFND | 1 | 0 | 5,623,816 | 0 | |
| Neumora Therapeutics, Inc. | COM | 640979100 | 24,431,168 | 1,849,445 | SH | DFND | 1 | 0 | 1,849,445 | 0 | |
| Procept BioRobotics Corporation | COM | 74276L105 | 28,678,073 | 357,939 | SH | DFND | 1 | 0 | 357,939 | 0 | |
| Protagonist Therapeutics Inc. | COM | 74366E102 | 110,213,235 | 2,449,183 | SH | DFND | 1 | 0 | 2,449,183 | 0 | |
| Rallybio Corporation | COM | 75120L100 | 4,254,545 | 3,636,363 | SH | DFND | 1 | 0 | 3,636,363 | 0 | |
| Rapport Therapeutics, Inc. | COM | 75383L102 | 51,160,084 | 2,498,051 | SH | DFND | 1 | 0 | 2,498,051 | 0 | |
| Senseonics Holdings, Inc. | COM | 81727U105 | 19,101 | 54,621 | SH | DFND | 1 | 0 | 54,621 | 0 | |
| Vor Biopharma, Inc. | COM | 929033108 | 752,261 | 1,074,658 | SH | DFND | 1 | 0 | 1,074,658 | 0 | |
| Xencor, Inc. | COM | 98401F105 | 15,043,527 | 748,062 | SH | DFND | 1 | 0 | 748,062 | 0 | |
| Standard BioTools Inc | COM | 34385P108 | 602,096 | 311,967 | SH | DFND | 0 | 311,967 | 0 | ||
