Northern Trust 8K northerntrust.com / © 2024 Northern Trust 2024 Annual Meeting Of Stockholders | NTRS 16 Apr 24

northerntrust.com / © 2024 Northern Trust 2 Forward-looking Statements This presentation may include statements which constitute “forward-looking statements” within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are identified typically by words or phrases such as “believe,” “expect,” “anticipate,” “intend,” “estimate,” “project,” “l ikely,” “plan,” “goal,” “target,” “strategy,” and similar expressions or future or conditional verbs such as “may,” “will,” “should,” “would,” and “could.” Forward-looking statements include statements, other than those related to historical facts, that relate to Northern Trust’s financial results and outlook, capital adequacy, dividend policy and share repurchase program, accounting estimates and assumptions, credit quality including allowance levels, future pension plan contributions, effective tax rate, anticipated expense levels, contingent l iabil it ies, acquisitions, strategies, market and industry trends, and expectations regarding the impact of accounting pronouncements and legislation. These statements are based on Northern Trust’s current beliefs and expectations of future events or future results and involve risks and uncertainties that are difficult to predict and subject to change. These statements are also based on assumptions about many important factors, including the factors discussed in Northern Trust’s most recent annual report on Form 10-K and other fi l ings with the U.S. Securities and Exchange Commission, all of which are available on Northern Trust’s website. We caution you not to place undue reliance on any forward-looking statement as actual results may differ materially from those expressed or implied by forward-looking statements. Northern Trust assumes no obligation to update its forward-looking statements.

northerntrust.com / © 2024 Northern Trust Our mission is to be our clients’ most trusted financial partner 3 Service Relentless drive to anticipate and exceed client expectations Expertise Resolving complex challenges with world class capabilities Integrity Consistently acting with the highest ethics, utmost honesty and unfailing reliability

4 Financial Performance: Full Year 2023 northerntrust.com / © 2024 Northern Trust *2023 Pre-tax Notable Items include $38.7 million severance-related charge; $25.6 million client capability charge; $12.8 million occupancy charge; $84.6 million FDIC special assessment; and $(169.5) million net investment security gains/losses. 2022 Pre-tax Notable Items include $44.1 million pension settlement charge; $32.0 million severance-related charge; $14.0 million occupancy charge; and $(214.0) million net investment security gains/losses. **Actual numbers for all periods, not % change. N/M = not meaningful All figures as of December 31, 2023. GAAP RESULTS INCLUDE IMPACT OF NOTABLE ITEMS* $ in mi l l ions (except EPS and as noted) FISCAL YEAR 2023 % CHANGE VS. 2022 Noninterest Income $4,792 (2)% Net Interest Income 1,982 +5% Total Revenue 6,774 - Provision for Credit Losses 24.5 N/M Total Noninterest Expense 5,284 +6% Provision for Income Taxes 358 (17)% Net Income 1,107 (17)% Diluted Earnings Per Share (EPS) $5.08 $6.14 Return on Average Common Equity (ROE)** 10.0% 12.7%

northerntrust.com / © 2024 Northern Trust 5 Balance Sheet and Capital Highlights NORTHERN TRUST CORPORATION REGULATORY CAPITAL HIGHLIGHTS STANDARDIZED APPROACH ADVANCED APPROACH MINIMUM REQUIREMENT Common Equity Tier 1 11.4% 13.4% 4.5% Tier 1 Capital 12.3% 14.5% 6.0% Total Capital 14.2% 16.5% 8.0% Tier 1 Leverage 8.1% 8.1% 4.0% Supplementary Leverage N/A 8.6% 3.0% All figures as of December 31, 2023.

northerntrust.com / © 2024 Northern Trust 6 Well-Positioned for Success Wealth Management Asset Servicing Asset Management $1.4 Trillion Assets Under Management $1.1 Trillion Client Assets & Liabilities* $15.4 Trillion Assets Under Custody/Administration *Wealth Management Client Assets & Liabilities = EOP Loans + EOP Deposits + AUM + AUC non-managed. AUC/A, AUM, Wealth Management Client Assets & Liabilities are as of December 31, 2023 and are rounded.

northerntrust.com / © 2024 Northern Trust Enduring Principles 13 Service Relentless drive to anticipate and exceed client expectations Expertise Resolving complex challenges with world class capabilities Integrity Consistently acting with the highest ethics, utmost honesty and unfailing reliability

northerntrust.com / © 2024 Northern Trust 15 Reconciliation of Non-GAAP Financial Measures The fo l l ow ing tab le p rov ides a reconc i l i a t ion o f re tu rn on average common equ i t y , p repared i n accordance w i th GAAP to such measure on an ad jus ted bas i s , exc lud ing ce r ta in no tab le i t ems , wh ich i s a non-GAAP f i nanc ia l measure . Re tu rn on average common equ i t y i s ca l cu la ted by d i v id ing ne t i ncome app l i cab le to common shareho lde rs by ave rage common shareho lde rs ’ equ i t y . Management be l i eves th i s p resen ta t i on p rov ides i nves to rs w i th a v iew more c lose l y a l i gned w i th how management v iews the o rgan iza t i on ’ s f i nanc ia l pe r fo rmance i n 2023 .

Northern Trust (NTRS) 8-KNORTHERN TRUST CORPORATION northerntrust.com / © 2024 Northern Trust 2024 Annual Meeting Of Stockholders