Fair Value Measurements (Details) € in Millions, £ in Millions, $ in Millions | Aug. 19, 2019USD ($) | Aug. 19, 2019GBP (£) | Dec. 31, 2020USD ($)units | Dec. 31, 2019USD ($) | Dec. 31, 2018USD ($) | Dec. 31, 2019EUR (€) |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Payments for Hedge, Investing Activities | | | $ 0 | $ 199 | $ 0 | |
Gain (Loss) on Cash Flow Hedge Ineffectiveness, Net | | | 29 | 34 | | |
Derivative, Notional Amount | | | 11,349 | 10,218 | | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax | | | 77 | (116) | | |
Cost of Goods and Services Sold | | | 3,465 | 3,116 | 2,813 | |
Derivative financial instruments | | | 60 | 54 | | |
Interest Expense | | | 361 | 473 | 241 | |
Other Operating Income (Expense), Net | | | (362) | 358 | | |
Gain (Loss) on Derivative Used in Net Investment Hedge, after Tax | | | 19 | 33 | | |
Foreign exchange (gain) loss | | | (32) | (358) | 11 | |
Derivative Asset, Fair Value, Gross Asset | | | 242 | 321 | | |
Derivative Liability, Fair Value, Gross Liability | | | 1,262 | 1,037 | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Equity Securities, FV-NI | | | 414 | 1 | | |
Derivative Asset | | | 109 | 216 | | |
Licensing arrangements, asset | | | 218 | 332 | | |
Business Combination, Contingent Consideration, Liability | | | 196 | 354 | 347 | |
Cash | | | 150 | 165 | | |
Proceeds from royalty rights transfer | | | 0 | 256 | 0 | |
Debt Instrument, Fair Value Disclosure | | | 10,774 | 11,020 | | |
Other Noncurrent Liabilities [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Licensing arrangements, liability | | | 253 | 374 | | |
November 2019 Aggregate Offering [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Long-term Debt | | | | 1,000 | | € 900 |
December 2027 Notes [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Long-term Debt | | | $ 1,105 | 1,011 | | |
Debt Instrument, Interest Rate, Stated Percentage | | | 0.625% | | | |
Licensing arrangement assets (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Discount Rate, Fair Value Input | | | 15.00% | | | |
Euro-denominated outstanding debt [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Debt Instrument, Fair Value Disclosure | | | $ 1,118 | 1,004 | | |
BTG Acquisition [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Proceeds from royalty rights transfer | | | 256 | | | |
Fair Value, Inputs, Level 3 [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Licensing arrangements, asset | | | 365 | | | |
Licensing arrangements, liability | | | 407 | | | |
Fair Value, Measurements, Recurring [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Money Market Funds, at Carrying Value | | | 1,584 | 50 | | |
Equity Securities, FV-NI | | | 414 | 1 | | |
Derivative Asset | | | 242 | 321 | | |
Licensing arrangements, asset | | | 365 | 518 | | |
Assets, Fair Value Disclosure | | | 2,605 | 890 | | |
Foreign Currency Contracts, Liability, Fair Value Disclosure | | | 1,262 | 1,037 | | |
Business Combination, Contingent Consideration, Liability | | | 196 | 354 | | |
Licensing arrangements, liability | | | 407 | 571 | | |
Financial and Nonfinancial Liabilities, Fair Value Disclosure | | | 1,865 | 1,963 | | |
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 1 [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Money Market Funds, at Carrying Value | | | 1,584 | 50 | | |
Equity Securities, FV-NI | | | 414 | 1 | | |
Derivative Asset | | | 0 | 0 | | |
Licensing arrangements, asset | | | 0 | 0 | | |
Assets, Fair Value Disclosure | | | 1,998 | 51 | | |
Foreign Currency Contracts, Liability, Fair Value Disclosure | | | 0 | 0 | | |
Business Combination, Contingent Consideration, Liability | | | 0 | 0 | | |
Licensing arrangements, liability | | | 0 | 0 | | |
Financial and Nonfinancial Liabilities, Fair Value Disclosure | | | 0 | 0 | | |
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 2 [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Money Market Funds, at Carrying Value | | | 0 | 0 | | |
Equity Securities, FV-NI | | | 0 | 0 | | |
Derivative Asset | | | 242 | 321 | | |
Licensing arrangements, asset | | | 0 | 0 | | |
Assets, Fair Value Disclosure | | | 242 | 321 | | |
Foreign Currency Contracts, Liability, Fair Value Disclosure | | | 1,262 | 1,037 | | |
Business Combination, Contingent Consideration, Liability | | | 0 | 0 | | |
Licensing arrangements, liability | | | 0 | 0 | | |
Financial and Nonfinancial Liabilities, Fair Value Disclosure | | | 1,262 | 1,037 | | |
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member] | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Money Market Funds, at Carrying Value | | | 0 | 0 | | |
Equity Securities, FV-NI | | | 0 | 0 | | |
Derivative Asset | | | 0 | 0 | | |
Licensing arrangements, asset | | | 365 | 518 | | |
Assets, Fair Value Disclosure | | | 365 | 518 | | |
Foreign Currency Contracts, Liability, Fair Value Disclosure | | | 0 | 0 | | |
Business Combination, Contingent Consideration, Liability | | | 196 | 354 | | |
Licensing arrangements, liability | | | 407 | 571 | | |
Financial and Nonfinancial Liabilities, Fair Value Disclosure | | | 603 | 925 | | |
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member] | Licensing arrangement assets (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Licensing arrangements, asset | | | 365 | 518 | 0 | |
Fair Value of Assets Acquired | | | | 567 | | |
Proceeds from Royalties Received | | | 175 | 52 | | |
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option | | | 22 | 3 | | |
Fair Value, Measurements, Recurring [Member] | Fair Value, Inputs, Level 3 [Member] | Licensing arrangement liabilities (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Licensing arrangements, liability | | | 407 | 571 | 0 | |
Fair Value of Assets Acquired | | | | 315 | | |
Proceeds from Royalties Received | | | | 256 | | |
Payments for Royalties | | | (186) | | | |
Increase (Decrease) in Fair Value Adjustments on Other Assets (Liabilities) Carried at Fair Value under Fair Value Option | | | 22 | | | |
Designated as Hedging Instrument [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Assets, at Fair Value | | | 162 | 288 | | |
Derivative Instruments in Hedges, Liabilities, at Fair Value | | | 1,191 | 1,009 | | |
Designated as Hedging Instrument [Member] | Other Noncurrent Liabilities [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Liabilities, at Fair Value | | | $ 1,094 | 998 | | |
Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Forward Currency Contracts, Time to Maturity | units | | | 60 | | | |
Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Other Noncurrent Assets [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Assets, at Fair Value | | | $ 109 | 216 | | |
Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Other Current Liabilities [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Liabilities, at Fair Value | | | 44 | 3 | | |
Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Other Noncurrent Liabilities [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Liabilities, at Fair Value | | | 54 | 8 | | |
Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Prepaid Expenses and Other Current Assets [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments in Hedges, Assets, at Fair Value | | | 53 | 72 | | |
Not Designated as Hedging Instrument [Member] | Other Nonoperating Income (Expense) [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Gain (Loss) on Foreign Currency Derivative Instruments Not Designated as Hedging Instruments | | | 73 | (343) | 41 | |
Foreign Currency Transaction Gain (Loss), before Tax | | | (105) | (15) | (30) | |
Foreign exchange (gain) loss | | | (32) | (358) | 11 | |
Net gain (loss) from foreign currency transaction exposures | | | 105 | 15 | 30 | |
Not Designated as Hedging Instrument [Member] | BTG Acquisition [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Payments for Hedge, Investing Activities | | | | 294 | | |
Not Designated as Hedging Instrument [Member] | BTG Acquisition [Member] | Other Nonoperating Income (Expense) [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Gain (Loss) on Foreign Currency Derivative Instruments Not Designated as Hedging Instruments | | | | (323) | 29 | |
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative, Notional Amount | | | 4,946 | 4,377 | | |
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Other Current Liabilities [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments Not Designated as Hedging Instruments, Liability, at Fair Value | | | 71 | 29 | | |
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Prepaid Expenses and Other Current Assets [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Instruments Not Designated as Hedging Instruments, Asset, at Fair Value | | | $ 79 | 33 | | |
Not Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | BTG Acquisition [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative, Cash Received on Hedge | $ 4,303 | £ 3,312 | | | | |
Weighted Average (Member) | Licensing arrangement assets (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Discount Rate, Fair Value Input | | | 15.00% | | | |
Weighted Average (Member) | Licensing arrangement liabilities (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Discount Rate, Fair Value Input | | | 13.00% | | | |
Minimum [Member] | Licensing arrangement liabilities (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Discount Rate, Fair Value Input | | | 12.00% | | | |
Maximum [Member] | Licensing arrangement liabilities (Member) | | | | | | |
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] | | | | | | |
Discount Rate, Fair Value Input | | | 15.00% | | | |
Cash Flow Hedging [Member] | Foreign Exchange Contract (Member) | Cost of Sales [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Foreign Currency Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months | | | $ 21 | | | |
Cash Flow Hedging [Member] | Interest Rate Contract [Member] | Interest Expense [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Interest Rate Cash Flow Hedge Gain (Loss) to be Reclassified During Next 12 Months, Net | | | (5) | | | |
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative, Notional Amount | | | 4,531 | 3,891 | | |
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Cost of Sales [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification and Tax | | | 99 | (150) | (167) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, Tax | | | (22) | 34 | 38 | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax | | | 77 | (117) | (130) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax | | | 83 | 73 | (19) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, Tax | | | 19 | 16 | (4) | |
Derivative financial instruments | | | (64) | (56) | 15 | |
Cash Flow Hedging [Member] | Designated as Hedging Instrument [Member] | Interest Rate Contract [Member] | Interest Expense [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification and Tax | | | 0 | 0 | (44) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, Tax | | | 0 | 0 | 10 | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), before Reclassification, after Tax | | | 0 | 0 | (34) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, before Tax | | | 5 | 3 | (1) | |
Other Comprehensive Income (Loss), Cash Flow Hedge, Gain (Loss), Reclassification, Tax | | | (1) | (1) | 0 | |
Derivative financial instruments | | | 4 | 2 | (1) | |
Net Investment Hedging [Member] | Foreign Exchange Contract (Member) | Interest Expense [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative Used in Net Investment Hedge Gain (Loss) to be Reclassified During Next 12 Months, Net | | | 13 | | | |
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative, Notional Amount | | | 1,004 | 953 | | |
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign Exchange Contract (Member) | Interest Expense [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), before Reclassification and Tax | | | (37) | (68) | (56) | |
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, Tax | | | 8 | 15 | 13 | |
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, after Tax | | | (29) | (53) | (43) | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), Reclassification, before Tax | | | (24) | 43 | 27 | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), after Reclassification, Tax | | | 5 | 10 | 6 | |
Gain (Loss) on Derivative Used in Net Investment Hedge, after Tax | | | (19) | 33 | $ 21 | |
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign currency denominated in debt [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Derivative, Notional Amount | | | 868 | 997 | | |
Net Investment Hedging [Member] | Designated as Hedging Instrument [Member] | Foreign currency denominated in debt [Member] | Interest Expense [Member] | | | | | | |
Derivative Instruments, Gain (Loss) [Line Items] | | | | | | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), before Reclassification and Tax | | | (89) | (14) | | |
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, Tax | | | 21 | 3 | | |
Other Comprehensive Income (Loss), Derivative, Excluded Component, Increase (Decrease), before Adjustments, after Tax | | | (68) | (11) | | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), Reclassification, before Tax | | | 0 | 0 | | |
Other Comprehensive Income (Loss), Net Investment Hedge, Gain (Loss), after Reclassification, Tax | | | 0 | 0 | | |
Gain (Loss) on Derivative Used in Net Investment Hedge, after Tax | | | $ 0 | $ 0 | | |