Okay. you, Thank Andy.
and results quarter fourth the year. to like the the of I'd full first, So review
a in fourth Similar a for sales sales the again, of QX prior net were a to result X.X% primarily currency-neutral year-over-year in $XXX.X our So $XXX.X basis. basis million. of biotech end XXXX a XXXX weakness It's decline markets, the of on impacting products. the revenue X.X% million versus decline and primarily on reported quarter of ongoing fourth the decline Life quarter, biopharma the and segment was quarter Science
demand In Science to addition, weak in products Life we experience continue China. for
macroeconomic think initiatives. local the in million COVID-related And sales, currency-neutral basis, a were well currency in in and year revenue, a the environment neutral. to and as and the which in decreased geographic in decreased immaterial the Europe X.X% some result $XX.X was then China COVID-related on both Made quarter prior I of as XXXX. extent, as of Asia. fourth Therefore, core revenue year-over-year flat Americas excludes relatively the sales
of $XXX.X on So XXXX $XXX.X a a QX sales for Life compared million quarter fourth grew in were million which a Science to and on XX.X% of in currency-neutral decline is basis. XXXX, the XX.X% basis reported
Science COVID-related currency-neutral of core for broad-based Excluding Life decline a revenue approximately experienced year-over-year sales XX%.
and finally, sales, mentioned faced decreased chromatography quarter due biopharma macroeconomic the In chromatography XXXX. business addition and quarter, burn-down excluding biotech, neutral. ddPCR, Life when compares the in the XX.X% sales markets China in Science process and related currency-neutral factors, sales conditions to a XX.X% back the difficult challenging QX Andy versus and process excluding revenue, on other soft year during qPCR the Science to Life ago basis COVID decreased underlying the And And currency Group period. and of
the growth product on $XXX reported regions. On from strong for growth currency-neutral we growth Group and Asia. which revenue, of to a back all Science reduction across $XXX.X sales Clinical Diagnostics Clinical year-over-year of was particular of Diagnostics quarter increased driven core year-over-year strength On group This Group by Diagnostics in the from compared sales geographic then sales in basis. were a basis, And a as X.X% Diagnostic basis as million, growth well primarily X a a geographic saw million Conversely, elevated basis, the COVID-related Life QX benefited core revenue excludes on XXXX. X.X% the broad-based X.X%. in orders. Diagnostics Fourth decreased Group. The revenue represents of Clinical diabetes Clinical
was the related XXXX quarter to million XX.X% in or to to and the the volume, QX were SG&A due decline impacts lower goods XX.X% of number to compared year-over-year margin of The gross of lower cost manufacturing mainly inflation QX factors, quarter XX.X% on $X.X XXXX. $XXX.X compares quarter was of gross as in fourth $XXX.X a SG&A sales a was was of or fourth The to of reserves. recorded XXXX. for in acquisitions due XX.X% lower employee-related quarter reported million in million For prior recorded and XXXX. million margin to of including the to $X.X a inventory facility by expenses compared company, offset Amortization QX million in lease And the of of SG&A impairment. GAAP total expense related $X.X in a million for dollar was expenses and partially amortization 'XX. in weaker $X.X versus QX the acquisitions basis
QX both the in $XX.X levels to of and of expenses. million million income XX.X% or million fourth of $XX.X quarter in $XXX.X million employee-related compared or was or of in quarter reflect Fourth of expense $XX.X The development X.X% expense and XXXX. lower QX project lower compared sales XX% was Research to or sales X.X% XXXX. sales sales of operating
are fair in substantially of to equity to line, reported Bio-Rad's Sartorius operating shares ownership results. holdings, the below market the AG related million Looking added security which change of value of income $XXX.X the
in $X.X primarily from of years to in mix the Tax compared interest was year in expense effective equity other tax the earnings. lower result unrealized and for was quarter securities in period the for During rate XX.X% The by quarter, of XXXX fourth were income the for other by of and increased net changes income XX.X% million geographical driven the rate rates same XXXX million both in other interest compared primarily of income gains last $X.X investments. driven XXXX. net a of to resulted
share of is, of the earnings diluted This $XXX.X again, change net Fourth income XXXX. valuation net of compared in $XXX.X largely changes income related to $XX.XX Holdings. QX share in diluted quarter per last million or or million of to was $XX.XX year from reported earnings Sartorius per
So are moving have income. well and non-GAAP items These unique certain non-GAAP atypical release. detailed reconciliation in and as both press a table items on gross other we On in impacted as the excluded the to the operating margins basis, that results.
the in versus fourth looking have QX non-GAAP goods, persistent benefit. of non-GAAP of These quarter. of of fourth quarter XXXX gross cost for the a margin restructuring small million and excluded the XX.X% of amortization intangibles the results $X.X XX.X% So a margin In gross of to we moved XXXX. at for exclusions
acquisition-related $X.X purchased $XXX,XXX XX% margin intangibles of non-GAAP of from $XXX.X was the in in non-GAAP XXXX products below QX value restructuring-related versus in of certain margin line, a costs. and excluded fourth of GAAP holdings in margin in X.X%, equity Non-GAAP adjustments XX.X% approved of the million And of XX.X% in diagnostics as million on items operating Europe Sartorius the and on on operating to $X.X which of result these sum basically have also operating excluded moving Non-GAAP of are a R&D restructuring XX.X% $X.X accumulated previously of $XXX,XXX loan in million operating the the expenses. R&D basis, to an And of quarter non-GAAP and have same a a SG&A, this increase XX.X% we basis and -- in fourth on non-GAAP SG&A a XXXX. we non-GAAP for cumulative venture fee receivable in In XXXX. QX non-GAAP registration million; XXXX basis. amortization basis, expense investments. excluded a on of vitro $XXX,XXX was We've the expenses in loss of quarter the XXXX. the compares quarterly
was compared effective of diluted earnings The by share primarily $X.XX period for and And finally, geographical rate was reserves XX.X% quarter for diluted fourth driven tax XX.X% a to in in of rate the non-GAAP income lower per fourth related per QX XXXX positions. quarter XXXX. in the XXXX mix release $XX.X was the share the The to of same XXXX or tax million of to non-GAAP $XX.X earnings certain compared million of $X.XX for of earnings XXXX. tax or net resolution of
a flat year COVID-related billion, XXXX is the sales in a were on or the basis a about XXXX results. reported the XXXX full sales X.X% So net year-over-year full $X.XXX year On on were full year to currency-neutral $XXX X.X% effectively XXXX a now decreased sales so to which million for excludes [ for billion $X decreased X.X%. Net compared revenue, million compared currency-neutral that COVID-related for as core full $X.XXX -- year in which basis, basis. decline ] XXXX. sales of
of Science the of year-over-year a results Life Group declined year $X.XXX segment. Now Blot. by year-over-year were When of revenue and for the qPCR Sales looking process at XXXX XX% COVID-related decline a sales, by sales currency-neutral basis. on decline core full excluding X.X%. driven majority was products year-over-year Science chromatography, Western billion, Life The currency-neutral
a year Europe declined COVID while basis. a a Clinical sales, core currency-neutral for posted full On X.X% Asia basis, represents Diagnostic which reminder a Science $X.XXX which excludes billion, on and geographic products Life the of modest growth. currency-neutral Sales growth the as in XXXX were Americas revenue,
basis, a offset year-over-year SG&A driven diabetes, million sales, The currency-neutral or XX.X% and by by clinical control cost in mainly sales blood million in costs. our infectious products, year the by was higher and grew SG&A partially COVID-related margin revenue leverage. was decline lease $XXX.X geographic was full regions. by excluding COVID XXXX. in Full lower employee-related diagnostics quality year non-GAAP implementation Asia, company was to When $XXX.X of X.X% fees, core of spend, expense or non-GAAP compared related XX.X% X year-over-year and was to was SAP decline offset compared The legal product sales lower higher growth discretionary typing clinical to inventory margin currency-neutral impairment sales, fixed Overall, reserves driven all XXXX. lower partially On XX.X% a mix, revenue disease across diagnostics, year gross in XX.X% growth core full products. and
Full year reflects of effects of and which X.X% year $XXX.X decline, million of XXXX, mix compares in tax in non-GAAP with and effective sales and rate sales year cost $XXX.X XX.X% or in consistent XX.X% compared revenue our XXXX range the of income operating full million R&D X.X% XX.X% lower to or full versus for was the in the absorption. XXXX fixed was non-GAAP lastly, was XXXX. non-GAAP guidance shifts XX% to And
and the cash was end to tax of sheet. primarily balance short-term moving the at $X.XXX So $X.XXX third was XXXX. change of quarter from at the on $X.XXX ] the cash investments of share and XXXX quarter The billion [ billion XXXX of due in XXXX end and of the at working investments capital payments. the short-term repurchases, third to of and Total compared to billion the timing end
concluded in a Bio-Rad's February maturing $XXX Yesterday, now agreement was $XXX line which provides just liquidity credit XXXX, year. million prior replaces in new million to mention, credit we financial in that of additional new a this maturing facility April enhances flexibility. And this of
Inventory the million the million primarily due level of was quarter slightly to from $XXX.X increased QX end higher in goods. finished a and of prior $XXX.X at to
to normal we of As the X quarters. X inventory we the chain next move from challenges years, anticipate on X to past continue decreasing more supply over to the levels
to of offset XXXX. $XX.X the For capital, increase which compares by the mainly of tax reflects working was activities from of in generated million This net million, quarter $XX in cash changes fourth timing operating payment. XXXX, QX
of the mainly This year million from full was operations reflects capital. XXXX, in in versus $XXX.X working $XXX.X generated cash For XXXX. changes million increase net
buyback share the to quarter, of with Again, the program. still for authorized repurchases further, our an $XXX million program. cost note under our approximately for million continue year. buybacks X,XXX,XXX so a the purchased be you understand have approximately to share we nearly totaled During as year that's shares useful just available And Board share we purchase of for per fourth $XXX full XXX,XXX million. for current price shares we $XXX average optimistic $XXX of stock total or Probably
shares XXX,XXX fourth for XXXX. stock EBITDA a comparison, of we quarter the XX.X%. in of or our of million the Adjusted $XXX for EBITDA $XXX.X about million, XXXX adjusted in was and quarter XXXX was XX.X% As sales fourth purchased of
fourth expenditures Full million year quarter dividend, for And million for $XX.X year $XXX.X $XXX.X million capital million. about fourth $XXX.X adjusted the the and including quarter spend the XXXX. were was XX.X% million full the to was CapEx Net Sartorius $XX.X year. in and depreciation XXXX for amortization and was EBITDA, of full finally, compared or XX.X%
for on So XXXX. non-GAAP guidance moving the to
As XXXX levels Life higher see we year as to Science Andy usual a outlook for transition business, of earlier, our and recovery for steady Diagnostics. growth with uncertainty alluded do than a
P&L muted as Russia. especially we a growth, the have that expense revenue and to point XXX relates overcome XXXX. to that basis in XXX Keep I headwinds continuing And expenses China difficult Given say need to be represents operating to and between will this expansion it's our think geopolitical year. impacting mind employee-related it issues, that we fair headwind margin somewhere in
However, as are our we and cost for positioned we focused on growth improving revenue as returns. structure, leverage remain well margin remain -- we operating
expect This loaded biotech Again, bit I revenue different on is to a think operating the first is Consequently, than particularly be pharma. market in line in in very the second and expected based and the normal revenue year. in certainly to in with first a XXXX the the back-end of recovery half the year, we anticipated of gross quarter, margins recovery year more kind gross usual normalization. do soft and improvements with half
and how revenue currency-neutral growth a X% growth kind expected we revenue currency-neutral growth be currency-neutral X%. be for year-over-year all the to in rolling with be Diagnostics X% preamble, between XXXX estimate we We're Group that guiding revenue X.X% is And see the a So of out. and Science and here's Life year The is to to X.X% group, overall. between X%. between
below was inflationary our working last back cost. from in realized level, the the X% over little quarters elevated of trends improvement backdrop price through year, which overall a the we corporate With at to
year, part out also to Science the manufacturing to December in but $X results. We noncore a price was really through mainly immaterial contract a of group. similar operations annually, sale like the This an achieve level prior call impact revenue a financial other of Life are to of realization contributed is this targeting had of business under million business that We'd acquisition. overall reported million $X our on
XX%. between to recovery Full is to be the range margin gross year first and the below sales is year. projected XX% volume. margin to and anticipated is non-GAAP projected with second and invest margin improved growth half approximately rate We projected the tax improvement the margin with our infrastructure full the be is year strategy. XX%, Gross XX% we non-GAAP in year expected CapEx to gross the million and million year anticipated non-GAAP to $XXX of by year be for XX.X% Full throughout continue half driven be to steady between between to $XXX XX.X% operating our full be multiyear estimate to support as
expected non-GAAP EBITDA, Sartorius between when to divined EBITDA the year dividend, be is and full be and the XX.X% Sartorius And we between adjusted finally, And include announced expected to excluding is reduced XX.X%. XX% recently XX%. the
a platforms I corporate our our SAP little we baseline most our all journey would chain So transitioned And on We for few global the successfully think we constraints, key remarks, we're our for as key progress in to of transformation. diagnostics feel outlook manufacturing Singapore resolved of macro XXXX, -- XXXX. make supply a implementation. realistic bit in a comments facility. We've variables, pandemic. say to accomplishments, important, in the prepared on just continue clear we completed we maybe concluding today's a I spite about transformation, a Bio-Rad's good ongoing have
a of X.X%, life over markets at grown And progress. X Certainly, year. to mention, that we we XXXX which help that I a Life to. might it's forward later do good we number making exciting lot us our back our we over has underlying Science, important think in grown business last compound of I looking feel at Overall, science in pipeline rate the note our mentioned, currency-neutral years, the X%. to think Andy recovering forward products we're including, has as I to have a look solid have think as addition, In look drive I to