Thank you, Adam.
a quarter guidance. discussion my results, a followed review in start our with with of by to conclude comments our each performance full of and XXXX year segment fourth Going our
to can reference, X.X% primarily included lower X.X%. the business our growth X.X% year, Base found Business Revenue COVID have last acquisitions, deck COVID that of information currency, constant revenue Business grew the For $X while the year to was supplemental Organically, down in and quarter an to on Base partially Base in be also organic increase Base by Investor we billion, was compared Business compared testing our additional last testing. offset website. Business impact XX%. for from grew due The the Relations
soft we've for was research experienced early our The laboratories million loss of to as development charge due the Operating million business impairment $XXX biotech quarter $XXX an related to markets.
of In addition, million special $XXX to the we spin-off related charges coated had Fortrea. and of acquisitions,
offset these testing. Business operating items adjusted margins income by COVID and $XXX the in and Excluding XX.X% income lower and and to operating amortization, LaunchPad of of line $XXX hospital in year. recently or The last costs year XX% stranded compared margin to was savings adjusted were million the the in completed quarter and higher mix was with of personnel or decrease benefit revenue due million demand Base impact last partnerships. as were
with stranded $XXX this Our cost year. our Launchpad million initiatives of savings per $XXX of target to million long-term $XXX and around million year delivered consistent reduction
The the primarily rate The for benefit credits. last earnings rate the tax and compared quarter adjusted XX.X% adjusted was to of R&D was XX.X% tax mix tax increased to the geographic from due year. lower
$XXX for of $X.XX We quarter, up loss to X% was quarter be adjusted impairment due lower early from due from XX%. ago. COVID last XXXX The year was expect flow approximately operations the tax a rate charge. in Fully a $XXX to year. million in were development the was quarter cash $X.XX flow reduction our cash the million to EPS in for diluted compared to EPS testing. Adjusted Operating the continuing
in the million Capital expenditures quarter. totaled $XXX
to million this acquisitions expenditures For X.X% million. quarter the operations year, from was in flow be X.X% Free the in capital in and paid expect cash XXXX. million were continuing company The revenue, approximately of invested dividends. $XX $XXX out for we $XXX and full
While by quarter. count million completed we repurchases approximately not in X.X use repurchase our share quarter, accelerated cash did we share the during the which for program, any reduced shares the share
end $XXX million year, At share the of of the we repurchase had authorization remaining.
costs, $XXX million full debt. stock $XXX invested from million paid paid million. free operations, on of the and out excluding company $X of spin-related The in down repurchased year, $XXX continuing was cash $XXX million For flow acquisitions, billion dividends, maturing
will supplement acquisition our a have to potential organic continue growth. We robust that pipeline of opportunities
share our program is allocation In important addition, strategy. to we that of an capital repurchase our believe continue part
At $X.X year-end, cash we with billion. had debt $XXX million of in
debt months adjusted X.Xx trailing was to gross leverage XX Our EBITDA.
to year Business Business volume COVID X.X% constrained The last the with Business X.X%. contributed mostly last $X.X was was up X.X% organic grew grew to to as our down the testing. X.X% grew Base Business Laboratories. while year while to due acquisitions year. Now contributing X.X%. that billion, organic was Price/mix increased to Diagnostics acquisitions revenue X.X% which X.X%. organic base the segment acquisition Base quarter Total X.X% Base COVID growth by with by by XX%. last compared an price/mix compared beginning I'll compared volume volume Business compared as increase contributed volume volume business last X.X% year, of increased X.X%, lower organic was X.X% to offset versus Base COVID lower was Base Base year, organic Revenue last testing, performance, last of increased testing organically an while increase review and X.X% year for Business compared the
to expect operating adjusted adjusted million operating acquisitions to income the costs, or COVID was in due reduction COVID million recently costs. in operating testing up to over partially offset the personnel year. in XX.X% demand, testing. was The organic benefit decrease from and $XXX income $XXX Diagnostics LaunchPad improve including to last XX.X% of of revenue a decrease or reduction the Business to quarter which compared due and closed by Base for which higher was in The health impact the due care-related margin hospital partnerships, higher savings, we time. were was mix income
I'll continued The by of in currency was of $XXX Services. Labs, was foreign to quarter review an the compared an revenue was to performance X.X% and growth early Revenue strength translation X% last X% XX% driven higher-than-normal Now X.X% Laboratory in was our Biopharma million, while increase development year Central revenue cancellations. for down increase due due of segment of X.X%. up to organic which
billion and income into billion, $X.X Biopharma with costs. the quarter stranded to to personnel a $X.X ended $XX LaunchPad for quarter million next increased offset million Adjusted XX was higher partially at of and quarter We months. the we Book-to-bill savings, expect due over this XX of operating last convert months and the approximately the to $X.XX was with trailing growth adjusted revenue of organic or for and X.XX. backlog income operating XX.X% backlog revenue XX.X% the or $XXX by year. compared margin
includes as Now for I'll currently which XXXX, full share cash and from The flow anticipated targeted allocation, exchange year effective full XX, dividends. the rates year. guidance, guidance with XXXX enterprise also repurchases acquisitions, free the of capital our for December discuss impact foreign assumes
We expect translation the basis grow of revenue currency to impact points. Enterprise to favorable includes XX from compared foreign XXXX. This X.X% X.X% to
impact The be revenue offset Diagnostics to annualization X.X% of expected were XXXX. to in of compared expect by be testing We lower XXXX. completed is X.X% around COVID from the $XXX acquisitions million that up to to
compared X.X% impact expect guidance to XXX points. the includes of foreign translation basis XXXX. currency positive We biopharma grow This revenue to X.X% from to
and early both to range. grow the guidance expect central labs segment within We development
LaunchPad diagnostics margins in XXXX driven up and to We savings. top in be XXXX growth expect and versus by Biopharma line
Our is an to of guidance growth at $XX.XX midpoint the EPS implied range for rate approximately adjusted with XX%. $XX.XX
that seasonality will not typical quarter. quarterly earnings we to due first in expect do by noting we guide performance, While to weather it's disruption to quarterly will worth $X.XX January in quarter that be below earnings the $X.XX impact
profitable implied midpoint approximately that billion is XX%. through rate while repurchase to for program that also to be cash be we will and supplement the growth, continued our In with share expect returning an strong $X between at growth summary, and $X.XX generation billion, flow cash our used to growth expected Free capital flow of drive shareholders to free acquisitions organic dividends.
will now questions. we Operator, take